Condition (MeSH)
Typhoid Fever
ClinicalTrials.gov lists 71 trials for Typhoid Fever or a narrower condition beneath it. Novartis has the most among industry and government lead sponsors, with 6.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
71 of the 71 trials are tagged with Typhoid Fever itself; the rest are tagged with a narrower condition beneath it.
When did Typhoid Fever trials start? (24)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 6
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 4 |
| 2024 | 1 |
| 2023 | 5 |
| 2022 | 6 |
| 2021 | 5 |
| 2020 | 3 |
| 2019 | 6 |
| 2018 | 4 |
| 2017 | 2 |
Showing 10 of 24 earlier years.
No forecast is made for this condition: it averages 3.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Typhoid Fever trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 11 |
| Phase 1/2 | 3 |
| Phase 2 | 14 |
| Phase 2/3 | 1 |
| Phase 3 | 9 |
| Phase 4 | 15 |
| Not applicable | 8 |
| Observational | 10 |
How many Typhoid Fever trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 2 |
| Recruiting | 4 |
| Active, not recruiting | 3 |
| Completed | 53 |
| Unknown status | 9 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Typhoid Fever trials? (7)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Novartis | 6 |
| Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 3 |
| GlaxoSmithKline | 3 |
| EuBiologics Co.,Ltd | 2 |
| National Institute of Allergy and Infectious Diseases (NIAID) | 2 |
Showing 5 of 7 sponsors.
Which drugs are being tested for Typhoid Fever? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| TYPHIM Vi (Salmonella typhi vaccine) | 4 |
| Typhoid Vaccine | 3 |
Interventions as named in the registry (13)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| I.V. Meropenem | 4 |
| 1% Azithromycin | 4 |
| Typhoid Vi vaccine | 4 |
| Vi-DT | 3 |
| Vi Polysaccharide (PS) vaccine | 3 |
Showing 5 of 13 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Typhoid Fever trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Pneumonia | 12 | 2 |
| Gastroenteritis | 6 | 1 |
| Upper Respiratory Tract Infection | 4 | 1 |
| Measles | 3 | 1 |
| Bronchiolitis | 2 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Typhoid Fever? (111)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
Showing 5 of 111 publications.
Prevalence (24)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Typhoid | Annual incidence | 1-9 / 1 000 000 | North America | Not stated | Exact |
| Typhoid | Annual incidence | >1 / 1000 | South East Asia | Not stated | Exact |
| Typhoid | Annual incidence | 1-5 / 10 000 | Oceania | Not stated | Exact |
| Typhoid | Annual incidence | 1-5 / 10 000 | Latin America | Not stated | Exact |
| Typhoid | Annual incidence | 1-5 / 10 000 | Africa | Not stated | Unspecified |
Showing 5 of 24 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Typhoid | 99745 | Exact | Orphadata Science knowledge files, Product 1 |
| Typhoid | 99745 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.