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Condition (MeSH)

Vomiting

ClinicalTrials.gov lists 1,344 trials for Vomiting or a narrower condition beneath it. Merck Sharp & Dohme LLC has the most among industry and government lead sponsors, with 30.

MeSH D014839 Pathological Conditions, Signs and Symptoms C23
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Phase 1 Phase 1 58 Phase 1/2 Phase 1/2 15 Phase 2 Phase 2 149 Phase 2/3 Phase 2/3 24 Phase 3 Phase 3 185 Phase 4 Phase 4 227 Not applicable Not applicable 502 Observational Observational 182 Phase 1 Phase 1 58 Phase 1/2 Phase 1/2 15 Phase 2 Phase 2 149 Phase 2/3 Phase 2/3 24 Phase 3 Phase 3 185 Phase 4 Phase 4 227 Not applicable Not applicable 502 Observational Observational 182

Trials per phase (log scale)

1 more section with rows

764 of the 1,344 trials are tagged with Vomiting itself; the rest are tagged with a narrower condition beneath it.

Get the Vomiting report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Vomiting trials start? (30)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 93

1996: 1 trials (Phase 3 1) 1997: 1 trials (Phase 3 1) 1999: 2 trials (Phase 2 2) 2000: 3 trials (Observational 1, Not applicable 1, Phase 3 1) 2001: 4 trials (Not applicable 1, Phase 3 2, Phase 2 1) 2002: 7 trials (Not applicable 3, Phase 4 1, Phase 3 3) 2003: 13 trials (Not applicable 1, Phase 4 5, Phase 3 2, Phase 2/3 1, Phase 2 3, Phase 1 1) 2004: 21 trials (Observational 1, Not applicable 8, Phase 4 3, Phase 3 2, Phase 2 4, Phase 1 3) 2005: 37 trials (Observational 1, Not applicable 8, Phase 4 5, Phase 3 7, Phase 2 11, Phase 1 5) 2006: 37 trials (Observational 2, Not applicable 5, Phase 4 5, Phase 3 11, Phase 2 7, Phase 1/2 2, Phase 1 5) 2007: 31 trials (Observational 2, Not applicable 7, Phase 4 11, Phase 3 3, Phase 2 4, Phase 1 4) 2008: 45 trials (Observational 6, Not applicable 13, Phase 4 11, Phase 3 10, Phase 2/3 1, Phase 2 2, Phase 1/2 2) 2009: 54 trials (Observational 4, Not applicable 14, Phase 4 8, Phase 3 11, Phase 2/3 1, Phase 2 11, Phase 1/2 1, Phase 1 4) 2010: 45 trials (Observational 4, Not applicable 15, Phase 4 6, Phase 3 6, Phase 2/3 2, Phase 2 8, Phase 1 4) 2011: 59 trials (Observational 6, Not applicable 17, Phase 4 11, Phase 3 11, Phase 2/3 1, Phase 2 8, Phase 1/2 1, Phase 1 4) 2012: 53 trials (Observational 7, Not applicable 14, Phase 4 12, Phase 3 12, Phase 2 5, Phase 1 3) 2013: 44 trials (Observational 10, Not applicable 14, Phase 4 3, Phase 3 9, Phase 2 7, Phase 1/2 1) 2014: 55 trials (Observational 6, Not applicable 17, Phase 4 8, Phase 3 13, Phase 2 9, Phase 1 2) 2015: 64 trials (Observational 6, Not applicable 18, Phase 4 13, Phase 3 12, Phase 2/3 3, Phase 2 8, Phase 1 4) 2016: 54 trials (Observational 15, Not applicable 14, Phase 4 12, Phase 3 6, Phase 2 5, Phase 1 2) 2017: 59 trials (Observational 8, Not applicable 24, Phase 4 13, Phase 3 5, Phase 2/3 2, Phase 2 5, Phase 1 2) 2018: 62 trials (Observational 9, Not applicable 28, Phase 4 10, Phase 3 6, Phase 2/3 2, Phase 2 6, Phase 1 1) 2019: 51 trials (Observational 7, Not applicable 19, Phase 4 15, Phase 3 5, Phase 2 5) 2020: 61 trials (Observational 12, Not applicable 20, Phase 4 12, Phase 3 3, Phase 2/3 1, Phase 2 8, Phase 1/2 1, Phase 1 4) 2021: 69 trials (Observational 12, Not applicable 35, Phase 4 10, Phase 3 6, Phase 2/3 1, Phase 2 3, Phase 1/2 1, Phase 1 1) 2022: 86 trials (Observational 12, Not applicable 43, Phase 4 10, Phase 3 9, Phase 2/3 4, Phase 2 7, Phase 1/2 1) 2023: 74 trials (Observational 11, Not applicable 40, Phase 4 8, Phase 3 7, Phase 2/3 1, Phase 2 3, Phase 1/2 2, Phase 1 2) 2024: 76 trials (Observational 10, Not applicable 40, Phase 4 6, Phase 3 12, Phase 2/3 4, Phase 2 3, Phase 1/2 1) 2025: 93 trials (Observational 12, Not applicable 50, Phase 4 14, Phase 3 5, Phase 2 8, Phase 1/2 1, Phase 1 3)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 74
2025 93
2024 76
2023 74
2022 86
2021 69
2020 61
2019 51
2018 62
2017 59

Forecast of the full-year count, planned starts included, not rows of this table: about 94 trials starting in 2026 and about 89 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 31 months from start to primary completion across 85 trials still running at the 2026-10-09 snapshot; registered median of 14 months across 910 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Vomiting trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 58
Phase 1/2 15
Phase 2 149
Phase 2/3 24
Phase 3 185
Phase 4 227
Not applicable 502
Observational 182
Expanded access 2

How many Vomiting trials are recruiting? (11)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 58
Recruiting 94
Enrolling by invitation 9
Active, not recruiting 15
Available 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Vomiting trials? (4)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Merck Sharp & Dohme LLC 30
GlaxoSmithKline 24
Helsinn Healthcare SA 13
Acacia Pharma Ltd 12

Which drugs are being tested for Vomiting? (6)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Aprepitant 83
GRANISETRON 48
DEXMEDETOMIDINE 21
FOSAPREPITANT (Emend) 20
GW679769 18

Interventions as named in the registry (9)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Dexamethasone/Dexamethasone acetate 155
Ondansetron - Parts A + B 143
I.V. palonosetron 63
IM olanzapine 31
Metclopramide 31

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Vomiting trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Febrile neutropenia 477 18
Neutropenia 241 28
Pneumonia 213 33
Vomiting 113 33
Gastroenteritis 111 10

Which publications cover Vomiting? (1,218)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (3)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages