Condition (MeSH)
Leukemia, T-Cell
ClinicalTrials.gov lists 222 trials for Leukemia, T-Cell or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 25.
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Trials per phase (log scale)
1 more section with rows
32 of the 222 trials are tagged with Leukemia, T-Cell itself; the rest are tagged with a narrower condition beneath it.
When did Leukemia, T-Cell trials start? (35)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
- Other (Unknown)
Top of scale: 19
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 8 |
| 2025 | 4 |
| 2024 | 6 |
| 2023 | 8 |
| 2022 | 5 |
| 2021 | 10 |
| 2020 | 9 |
| 2019 | 7 |
| 2018 | 2 |
| 2017 | 4 |
Showing 10 of 35 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 10 trials starting in 2026 and about 8 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 36 months from start to primary completion across 28 trials still running at the 2026-10-09 snapshot; registered median of 39 months across 150 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Leukemia, T-Cell trials in? (9)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 73 |
| Phase 1/2 | 28 |
| Phase 2 | 56 |
| Phase 2/3 | 5 |
| Phase 3 | 16 |
| Phase 4 | 1 |
| Not applicable | 16 |
| Observational | 26 |
| Unknown | 1 |
How many Leukemia, T-Cell trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 3 |
| Recruiting | 33 |
| Active, not recruiting | 8 |
| Completed | 119 |
| Suspended | 2 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Leukemia, T-Cell trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Cancer Institute (NCI) | 25 |
| European Organisation for Research and Treatment of Cancer - EORTC | 4 |
| Children's Oncology Group | 3 |
Which drugs are being tested for Leukemia, T-Cell? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Cytoxan | 22 |
| Melphalan | 7 |
Interventions as named in the registry (13)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| SQ Fludarabine | 24 |
| Peripheral blood stem cell transplantation | 21 |
| Cyclosporine 0.05% | 17 |
| Total Body Irradiation | 16 |
| Mofetil Mycophenolate | 16 |
Showing 5 of 13 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Leukemia, T-Cell trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| 1 yr TRM | 93 | 1 |
| Neutropenia | 39 | 3 |
| Anemia | 31 | 3 |
| Sepsis | 30 | 9 |
| Febrile neutropenia | 27 | 9 |
Showing 5 of 10 adverse events.
Which publications cover Leukemia, T-Cell? (18)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| SF3B1 homeostasis is critical for survival and therapeutic response in T cell leukemia. | Science advances | 2022 | Yes |
| Guidelines for the management of mature T-cell and NK-cell neoplasms (excluding cutaneous T-cell lymphoma). | British journal of haematology | 2011 | Yes |
| The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia. | Cancer cell | 2010 | Yes |
| Recent advances in adult T-cell leukemia therapy: focus on a new anti-transferrin receptor monoclonal antibody. | Leukemia | 2008 | Yes |
| Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research | 2006 | Yes |
Showing 5 of 18 publications.
Sub-conditions in MeSH (3)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.