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Condition (MeSH)

Choroid Plexus Neoplasms

ClinicalTrials.gov lists 86 trials for Choroid Plexus Neoplasms or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 18.

MeSH D016545 Neoplasms Neoplasm C04 C10
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Phase 1 Phase 1 43 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 11 Phase 3 Phase 3 7 Not applicable Not applicable 7 Observational Observational 16 Phase 1 Phase 1 43 Phase 1/2 Phase 1/2 2 Phase 2 Phase 2 11 Phase 3 Phase 3 7 Not applicable Not applicable 7 Observational Observational 16

Trials per phase (log scale)

85 of the 86 trials are tagged with Choroid Plexus Neoplasms itself; the rest are tagged with a narrower condition beneath it.

Get the Choroid Plexus Neoplasms report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Choroid Plexus Neoplasms trials start? (24)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 3
  • Not applicable
  • Observational

Top of scale: 11

1992: 2 trials (Observational 1, Phase 2 1) 1994: 2 trials (Phase 1 2) 1996: 2 trials (Not applicable 1, Phase 1 1) 1997: 2 trials (Phase 2 1, Phase 1 1) 1998: 3 trials (Phase 2 1, Phase 1 2) 1999: 4 trials (Phase 2 1, Phase 1 3) 2000: 6 trials (Phase 2 2, Phase 1/2 1, Phase 1 3) 2001: 5 trials (Observational 2, Phase 2 1, Phase 1 2) 2002: 6 trials (Phase 1 6) 2003: 3 trials (Observational 1, Phase 2 1, Phase 1 1) 2004: 5 trials (Observational 3, Phase 3 1, Phase 1 1) 2005: 11 trials (Observational 2, Not applicable 1, Phase 3 1, Phase 1 7) 2006: 3 trials (Observational 1, Phase 1 2) 2007: 5 trials (Phase 3 1, Phase 2 2, Phase 1 2) 2008: 6 trials (Observational 2, Phase 3 1, Phase 1/2 1, Phase 1 2) 2009: 3 trials (Phase 3 1, Phase 1 2) 2010: 5 trials (Not applicable 1, Phase 3 1, Phase 1 3) 2011: 2 trials (Not applicable 2) 2013: 3 trials (Not applicable 1, Phase 3 1, Phase 1 1) 2014: 2 trials (Not applicable 1, Phase 1 1) 2017: 2 trials (Observational 1, Phase 2 1) 2020: 1 trials (Phase 1 1) 2023: 1 trials (Observational 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 2
2023 1
2020 1
2017 2
2014 2
2013 3
2011 2
2010 5
2009 3
2008 6

Showing 10 of 24 earlier years.

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No forecast is made for this condition: it averages 0.6 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Choroid Plexus Neoplasms trials in? (6)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 43
Phase 1/2 2
Phase 2 11
Phase 3 7
Not applicable 7
Observational 16

How many Choroid Plexus Neoplasms trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1
Recruiting 2
Enrolling by invitation 1
Active, not recruiting 1
Completed 54

Showing 5 of 8 statuses.

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Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Choroid Plexus Neoplasms trials? (4)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 18
Pediatric Brain Tumor Consortium 12
Children's Oncology Group 7
National Institutes of Health Clinical Center (CC) 5

Which drugs are being tested for Choroid Plexus Neoplasms? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Cytoxan 8
O6-Benzylguanine 3
Irinotecan 3
Thiotepa 3

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
SOC: Temozolomide 13
or carboplatin 11
Filgrastime (G-CSF) 9
Etoposid 8
Peripheral blood stem cell transplantation 7

Showing 5 of 11 interventions.

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These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Choroid Plexus Neoplasms trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
General disorders and administration site conditions - Other, specify: Disease Progression 13 1
Vomiting 11 4
Neoplasms benign, malignant and unspecified (incl cysts and polyps) - Other, specify: 10 1
Seizure 10 4
Hydrocephalus 6 2

Showing 5 of 10 adverse events.

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Which publications cover Choroid Plexus Neoplasms? (5)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Atypical choroid plexus papilloma: clinical experience in the CPT-SIOP-2000 study. Journal of neuro-oncology 2009 Yes
Malignancy-associated vessel tortuosity: a computer-assisted, MR angiographic study of choroid plexus carcinoma in genetically engineered mice. AJNR. American journal of neuroradiology 2006 Yes
Multiple epidural hematomas and hemodynamic collapse caused by a subgaleal drain and suction-induced intracranial hypotension: case report. Neurosurgery 2011 No
Pegylated-liposomal doxorubicin and oral topotecan in eight children with relapsed high-grade malignant brain tumors. Journal of neuro-oncology 2008 No
Phase I trial of intrathecal spartaject busulfan in children with neoplastic meningitis: a Pediatric Brain Tumor Consortium Study (PBTC-004). Clinical cancer research : an official journal of the American Association for Cancer Research 2006 No

Prevalence (2)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Choroid plexus tumor Annual incidence <1 / 1 000 000 United States US Exact
Choroid plexus tumor Annual incidence <1 / 1 000 000 United States US Exact

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Choroid plexus tumor 251896 Exact Orphadata Science knowledge files, Product 1
Choroid plexus tumor 251896 Exact Orphanet Rare Disease Ontology (ORDO)

Sub-conditions in MeSH (1)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

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