Condition (MeSH)
Malaria, Cerebral
ClinicalTrials.gov lists 14 trials for Malaria, Cerebral or a narrower condition beneath it. U.S. Army Medical Research and Development Command has the most among industry and government lead sponsors, with 2.
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Trials per phase
14 of the 14 trials are tagged with Malaria, Cerebral itself; the rest are tagged with a narrower condition beneath it.
When did Malaria, Cerebral trials start? (11)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Not applicable
- Observational
- Unknown
Top of scale: 2
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2022 | 2 |
| 2018 | 1 |
| 2014 | 1 |
| 2013 | 1 |
| 2012 | 1 |
| 2011 | 1 |
| 2008 | 1 |
| 2007 | 2 |
| 2006 | 1 |
| 2004 | 1 |
Showing 10 of 11 earlier years.
No forecast is made for this condition: it averages 0.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Malaria, Cerebral trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 2 |
| Phase 1/2 | 2 |
| Phase 2 | 2 |
| Phase 2/3 | 1 |
| Phase 3 | 4 |
| Not applicable | 1 |
| Observational | 1 |
| Unknown | 1 |
How many Malaria, Cerebral trials are recruiting? (3)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 1 |
| Completed | 10 |
| Unknown status | 3 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Malaria, Cerebral trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| U.S. Army Medical Research and Development Command | 2 |
| VisionQuest Biomedical LLC | 1 |
Which drugs are being tested for Malaria, Cerebral? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| 6-diazo-5-oxo-L-norleucine (DON) | 1 |
| EPOETIN ALFA | 1 |
Interventions as named in the registry (7)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Intravenous Artesunate | 2 |
| Levetiracetam XR | 2 |
| 20% mannitol | 1 |
| mechanical ventilation (MV) | 1 |
| Intrarectal quinine | 1 |
Showing 5 of 7 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Malaria, Cerebral trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| death | 6 | 1 |
| elevated AST | 5 | 1 |
| Sepsis | 4 | 1 |
| Respiratory problems from ventilator | 3 | 1 |
| respiratory suppression or aspiration | 3 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Malaria, Cerebral? (65)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| DON in pediatric cerebral malaria, a phase I/IIA dose-escalation safety study: study protocol for a clinical trial. | Trials | 2024 | Yes |
| Impact of Oxidative Stress on Risk of Death and Readmission in African Children With Severe Malaria: A Prospective Observational Study. | The Journal of infectious diseases | 2022 | Yes |
| Delayed iron improves iron status without altering malaria risk in severe malarial anemia. | The American journal of clinical nutrition | 2020 | Yes |
| EEG markers predictive of epilepsy risk in pediatric cerebral malaria - A feasibility study. | Epilepsy & behavior : E&B | 2020 | Yes |
| A clinical trial of enteral Levetiracetam for acute seizures in pediatric cerebral malaria. | BMC pediatrics | 2019 | Yes |
Showing 5 of 65 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.