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Condition (MeSH)

Gliosarcoma

ClinicalTrials.gov lists 487 trials for Gliosarcoma or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 94.

MeSH D018316 Neoplasms Neoplasm C04 Listed by Orphanet as a rare disease
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Phase 1 Phase 1 175 Phase 1/2 Phase 1/2 80 Phase 2 Phase 2 178 Phase 2/3 Phase 2/3 2 Phase 3 Phase 3 19 Not applicable Not applicable 18 Observational Observational 15 Phase 1 Phase 1 175 Phase 1/2 Phase 1/2 80 Phase 2 Phase 2 178 Phase 2/3 Phase 2/3 2 Phase 3 Phase 3 19 Not applicable Not applicable 18 Observational Observational 15

Trials per phase (log scale)

487 of the 487 trials are tagged with Gliosarcoma itself; the rest are tagged with a narrower condition beneath it.

Get the Gliosarcoma report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Gliosarcoma trials start? (35)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Not applicable
  • Observational

Top of scale: 34

1991: 1 trials (Phase 1 1) 1993: 2 trials (Phase 1/2 1, Phase 1 1) 1994: 6 trials (Phase 3 1, Phase 2 2, Phase 1 3) 1995: 4 trials (Observational 1, Phase 2 1, Phase 1 2) 1996: 6 trials (Not applicable 1, Phase 2 2, Phase 1 3) 1997: 11 trials (Phase 2 6, Phase 1/2 1, Phase 1 4) 1998: 14 trials (Not applicable 1, Phase 3 2, Phase 2 3, Phase 1/2 3, Phase 1 5) 1999: 19 trials (Phase 3 1, Phase 2 9, Phase 1/2 1, Phase 1 8) 2000: 26 trials (Phase 3 1, Phase 2 9, Phase 1/2 11, Phase 1 5) 2001: 23 trials (Observational 1, Not applicable 1, Phase 3 1, Phase 2 11, Phase 1/2 3, Phase 1 6) 2002: 31 trials (Observational 1, Phase 3 2, Phase 2 8, Phase 1/2 6, Phase 1 14) 2003: 12 trials (Observational 1, Phase 2 6, Phase 1/2 1, Phase 1 4) 2004: 21 trials (Observational 2, Not applicable 1, Phase 2 8, Phase 1/2 3, Phase 1 7) 2005: 34 trials (Observational 2, Not applicable 2, Phase 3 1, Phase 2 12, Phase 1/2 6, Phase 1 11) 2006: 29 trials (Observational 2, Not applicable 2, Phase 3 2, Phase 2 13, Phase 1/2 5, Phase 1 5) 2007: 32 trials (Observational 1, Phase 3 2, Phase 2 16, Phase 1/2 4, Phase 1 9) 2008: 28 trials (Observational 1, Not applicable 2, Phase 3 1, Phase 2 15, Phase 1/2 1, Phase 1 8) 2009: 27 trials (Phase 3 1, Phase 2 12, Phase 1/2 4, Phase 1 10) 2010: 28 trials (Not applicable 1, Phase 2 10, Phase 1/2 5, Phase 1 12) 2011: 15 trials (Observational 1, Not applicable 1, Phase 3 1, Phase 2 6, Phase 1/2 1, Phase 1 5) 2012: 13 trials (Phase 2 5, Phase 1/2 5, Phase 1 3) 2013: 16 trials (Not applicable 1, Phase 2 6, Phase 1/2 4, Phase 1 5) 2014: 11 trials (Not applicable 2, Phase 2/3 1, Phase 2 1, Phase 1/2 3, Phase 1 4) 2015: 12 trials (Phase 3 1, Phase 2 4, Phase 1/2 2, Phase 1 5) 2016: 8 trials (Phase 2 1, Phase 1/2 2, Phase 1 5) 2017: 9 trials (Not applicable 1, Phase 2 2, Phase 1/2 2, Phase 1 4) 2018: 7 trials (Not applicable 1, Phase 2 2, Phase 1 4) 2019: 7 trials (Phase 2 3, Phase 1 4) 2020: 7 trials (Phase 2/3 1, Phase 1/2 2, Phase 1 4) 2021: 4 trials (Phase 2 1, Phase 1 3) 2022: 4 trials (Phase 3 1, Phase 1/2 2, Phase 1 1) 2023: 5 trials (Observational 1, Phase 2 1, Phase 1 3) 2024: 2 trials (Observational 1, Phase 2 1) 2025: 4 trials (Phase 1 4)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 3
2025 4
2024 2
2023 5
2022 4
2021 4
2020 7
2019 7
2018 7
2017 9

No forecast is made for this condition: it averages 3.8 trial starts a year over the five years to September, under the 5 a year the method needs.

Prediction, not a registry value: median of 36 months from start to primary completion across 14 trials still running at the 2026-10-09 snapshot; registered median of 46 months across 393 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Gliosarcoma trials in? (7)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 175
Phase 1/2 80
Phase 2 178
Phase 2/3 2
Phase 3 19
Not applicable 18
Observational 15

How many Gliosarcoma trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 2
Recruiting 12
Active, not recruiting 20
Completed 340
Suspended 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Gliosarcoma trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 94
European Organisation for Research and Treatment of Cancer - EORTC 13
Radiation Therapy Oncology Group 10

Which drugs are being tested for Gliosarcoma? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Irinotecan 20
O6-Benzylguanine 12
THALIDOMIDE 8
Temsirolimus 8

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
SOC: Temozolomide 119
Radiation Therapy 81
Bevacizumab 1 35
Carmustin 24
Adjuvant Therapy 19

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Gliosarcoma trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Seizure 393 73
Platelet count decreased 317 32
Fatigue 248 49
Confusion 155 46
Lymphopenia 153 12

Which publications cover Gliosarcoma? (14)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Prevalence (3)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Gliosarcoma Annual incidence <1 / 1 000 000 Europe Not stated Unspecified
Gliosarcoma Annual incidence <1 / 1 000 000 Europe Not stated Exact
Gliosarcoma Annual incidence <1 / 1 000 000 Europe Not stated Exact

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Gliosarcoma 251576 Exact Orphadata Science knowledge files, Product 1
Gliosarcoma 251576 Exact Orphanet Rare Disease Ontology (ORDO)

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: sub-conditions in mesh.

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