Condition (MeSH)
Gingival Overgrowth
ClinicalTrials.gov lists 30 trials for Gingival Overgrowth or a narrower condition beneath it. CENTOGENE GmbH Rostock has the most among industry and government lead sponsors, with 1.
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Trials per phase (log scale)
18 of the 30 trials are tagged with Gingival Overgrowth itself; the rest are tagged with a narrower condition beneath it.
When did Gingival Overgrowth trials start? (16)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 2
- Phase 3
- Not applicable
- Observational
Top of scale: 3
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 3 |
| 2024 | 3 |
| 2023 | 2 |
| 2022 | 3 |
| 2021 | 3 |
| 2020 | 1 |
| 2019 | 3 |
| 2018 | 2 |
| 2017 | 2 |
Showing 10 of 16 earlier years.
No forecast is made for this condition: it averages 2.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 1 trial still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Gingival Overgrowth trials in? (5)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 1 |
| Phase 3 | 2 |
| Not applicable | 21 |
| Observational | 4 |
How many Gingival Overgrowth trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 1 |
| Enrolling by invitation | 1 |
| Completed | 24 |
| Terminated | 1 |
| Unknown status | 3 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Gingival Overgrowth trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| CENTOGENE GmbH Rostock | 1 |
Which drugs are being tested for Gingival Overgrowth? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Platelet Rich Fibrin | 1 |
| Hypochlorous Acid | 1 |
| Folic (or folinic) acid | 1 |
Interventions as named in the registry (12)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Injectable Platelet Rich Fibrin | 2 |
| Control (placebo) group | 2 |
| Low Level Laser Therapy | 1 |
| PRF group | 1 |
| Hyaluronic acid 1% | 1 |
Showing 5 of 12 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Gingival Overgrowth? (23)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Loss of TBC1D2B causes a progressive neurological disorder with gingival overgrowth. | European journal of human genetics : EJHG | 2024 | Yes |
| Gingivectomy with Diode Laser Versus the Conventional Scalpel Surgery and Nonsurgical Periodontal Therapy in Treatment of Orthodontic Treatment-Induced Gingival Enlargement: A Systematic Review. | Photobiomodulation, photomedicine, and laser surgery | 2023 | Yes |
| Gingival overgrowth: Part 1: aetiology and clinical diagnosis. | British dental journal | 2017 | Yes |
| Gingival overgrowth: Part 2: management strategies. | British dental journal | 2017 | Yes |
| Association between gingivitis and anterior gingival enlargement in subjects undergoing fixed orthodontic treatment. | Dental press journal of orthodontics | 2014 | Yes |
Showing 5 of 23 publications.
Sub-conditions in MeSH (2)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, and rare-disease identity.