Condition (MeSH)
Spondylarthritis
ClinicalTrials.gov lists 1,256 trials for Spondylarthritis or a narrower condition beneath it. Novartis Pharmaceuticals has the most among industry and government lead sponsors, with 47.
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Trials per phase (log scale)
1 more section with rows
195 of the 1,256 trials are tagged with Spondylarthritis itself; the rest are tagged with a narrower condition beneath it.
When did Spondylarthritis trials start? (35)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 93
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 71 |
| 2025 | 76 |
| 2024 | 75 |
| 2023 | 72 |
| 2022 | 75 |
| 2021 | 93 |
| 2020 | 69 |
| 2019 | 82 |
| 2018 | 63 |
| 2017 | 71 |
Showing 10 of 35 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 87 trials starting in 2026 and about 78 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 36 months from start to primary completion across 104 trials still running at the 2026-10-09 snapshot; registered median of 22 months across 780 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Spondylarthritis trials in? (9)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 46 |
| Phase 1/2 | 9 |
| Phase 2 | 108 |
| Phase 2/3 | 15 |
| Phase 3 | 191 |
| Phase 4 | 132 |
| Not applicable | 266 |
| Observational | 487 |
| Expanded access | 2 |
How many Spondylarthritis trials are recruiting? (11)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 66 |
| Recruiting | 153 |
| Enrolling by invitation | 10 |
| Active, not recruiting | 50 |
| Available | 1 |
Showing 5 of 11 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Spondylarthritis trials? (12)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Novartis Pharmaceuticals | 47 |
| Pfizer | 39 |
| AbbVie | 36 |
| Amgen | 23 |
| Janssen Research & Development, LLC | 23 |
Showing 5 of 12 sponsors.
Which drugs are being tested for Spondylarthritis? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| INFLIXIMAB | 39 |
| (CP-6890,550) Tofacitinib | 19 |
Interventions as named in the registry (13)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| 1=Etanercept | 64 |
| Adalimumab-US | 63 |
| Secukinmab | 56 |
| HD- Methotrexate (MTX) | 31 |
| SC golimumab | 29 |
Showing 5 of 13 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Spondylarthritis trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Pneumonia | 245 | 80 |
| Osteoarthritis | 224 | 68 |
| Cholelithiasis | 111 | 49 |
| Atrial fibrillation | 104 | 41 |
| Myocardial infarction | 99 | 45 |
Showing 5 of 10 adverse events.
Which publications cover Spondylarthritis? (273)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Juvenile Spondyloarthritis Disease Activity Index Validation in Enthesitis-Related Arthritis and Juvenile Psoriatic Arthritis in a Prospective Clinical Trial Setting. | The Journal of rheumatology | 2026 | Yes |
| Comparison of group versus individual patient education for promoting safety skills of patients with autoimmune rheumatic diseases treated with biologics: a multicentre randomised controlled trial. | Clinical rheumatology | 2025 | Yes |
| Efficacy and safety of jaktinib hydrochloride tablets in active axial spondyloarthritis: a multicentre, randomised, double-blind, placebo-controlled phase II clinical trial. | RMD open | 2025 | Yes |
| Influence of sacroiliac joint variation on clinical features of axial spondyloarthritis: a comparative analysis. | RMD open | 2025 | Yes |
| A combined analysis of spinal mobility and gait spatiotemporal parameters in axial spondyloarthritis using wearable sensors. | Clinical biomechanics (Bristol, Avon) | 2025 | Yes |
Showing 5 of 273 publications.
Sub-conditions in MeSH (2)
MeSH descendants one level down with at least one trial, most trials first.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and rare-disease identity.