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Condition (MeSH)

Spondylarthropathies

ClinicalTrials.gov lists 1,141 trials for Spondylarthropathies or a narrower condition beneath it. Novartis Pharmaceuticals has the most among industry and government lead sponsors, with 47.

MeSH D025242 Musculoskeletal Diseases C05
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Phase 1 Phase 1 44 Phase 1/2 Phase 1/2 8 Phase 2 Phase 2 106 Phase 2/3 Phase 2/3 15 Phase 3 Phase 3 189 Phase 4 Phase 4 119 Not applicable Not applicable 222 Observational Observational 436 Phase 1 Phase 1 44 Phase 1/2 Phase 1/2 8 Phase 2 Phase 2 106 Phase 2/3 Phase 2/3 15 Phase 3 Phase 3 189 Phase 4 Phase 4 119 Not applicable Not applicable 222 Observational Observational 436

Trials per phase (log scale)

1 more section with rows

66 of the 1,141 trials are tagged with Spondylarthropathies itself; the rest are tagged with a narrower condition beneath it.

Get the Spondylarthropathies report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Spondylarthropathies trials start? (35)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 82

1991: 1 trials (Observational 1) 1993: 1 trials (Not applicable 1) 1994: 1 trials (Observational 1) 1995: 3 trials (Observational 2, Phase 2 1) 1996: 1 trials (Phase 2 1) 1997: 1 trials (Not applicable 1) 1998: 2 trials (Observational 1, Not applicable 1) 1999: 2 trials (Observational 1, Phase 2 1) 2000: 2 trials (Observational 1, Phase 3 1) 2001: 1 trials (Phase 3 1) 2002: 12 trials (Observational 2, Phase 4 1, Phase 3 4, Phase 2/3 2, Phase 2 2, Phase 1 1) 2003: 13 trials (Observational 5, Phase 3 5, Phase 2 3) 2004: 18 trials (Observational 9, Phase 4 4, Phase 3 3, Phase 2 1, Phase 1 1) 2005: 20 trials (Observational 4, Not applicable 1, Phase 4 6, Phase 3 4, Phase 2/3 1, Phase 2 3, Phase 1/2 1) 2006: 21 trials (Observational 8, Phase 4 6, Phase 3 5, Phase 2 1, Phase 1 1) 2007: 24 trials (Observational 11, Not applicable 1, Phase 4 6, Phase 3 2, Phase 2/3 1, Phase 2 2, Phase 1 1) 2008: 28 trials (Observational 10, Not applicable 1, Phase 4 9, Phase 3 4, Phase 2/3 1, Phase 2 2, Phase 1 1) 2009: 24 trials (Observational 8, Not applicable 1, Phase 4 2, Phase 3 5, Phase 2 6, Phase 1/2 1, Phase 1 1) 2010: 35 trials (Observational 11, Not applicable 1, Phase 4 3, Phase 3 14, Phase 2 5, Phase 1 1) 2011: 30 trials (Observational 12, Not applicable 3, Phase 4 2, Phase 3 7, Phase 2 4, Phase 1 2) 2012: 32 trials (Observational 16, Not applicable 3, Phase 4 3, Phase 3 8, Phase 2 1, Phase 1 1) 2013: 37 trials (Observational 15, Not applicable 7, Phase 4 3, Phase 3 9, Phase 2 3) 2014: 45 trials (Observational 11, Not applicable 10, Phase 4 4, Phase 3 14, Phase 2 2, Phase 1/2 1, Phase 1 3) 2015: 60 trials (Observational 26, Not applicable 10, Phase 4 3, Phase 3 12, Phase 2 8, Phase 1 1) 2016: 54 trials (Observational 13, Not applicable 7, Phase 4 12, Phase 3 14, Phase 2/3 1, Phase 2 7) 2017: 62 trials (Observational 19, Not applicable 14, Phase 4 2, Phase 3 12, Phase 2/3 2, Phase 2 10, Phase 1/2 1, Phase 1 2) 2018: 55 trials (Observational 22, Not applicable 12, Phase 4 8, Phase 3 5, Phase 2/3 1, Phase 2 3, Phase 1 4) 2019: 72 trials (Observational 31, Not applicable 13, Phase 4 8, Phase 3 14, Phase 2 2, Phase 1 4) 2020: 59 trials (Observational 27, Not applicable 14, Phase 4 2, Phase 3 7, Phase 2/3 1, Phase 2 6, Phase 1 2) 2021: 82 trials (Observational 33, Not applicable 21, Phase 4 7, Phase 3 9, Phase 2/3 1, Phase 2 6, Phase 1/2 1, Phase 1 4) 2022: 68 trials (Observational 30, Not applicable 20, Phase 4 3, Phase 3 3, Phase 2/3 1, Phase 2 7, Phase 1 4) 2023: 68 trials (Observational 33, Not applicable 16, Phase 4 6, Phase 3 9, Phase 2 3, Phase 1 1) 2024: 68 trials (Observational 25, Not applicable 22, Phase 4 3, Phase 3 8, Phase 2/3 1, Phase 2 6, Phase 1 3) 2025: 69 trials (Observational 25, Not applicable 23, Phase 4 6, Phase 3 7, Phase 2/3 1, Phase 2 3, Phase 1/2 2, Phase 1 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 66
2025 69
2024 68
2023 68
2022 68
2021 82
2020 59
2019 72
2018 55
2017 62

Forecast of the full-year count, planned starts included, not rows of this table: about 81 trials starting in 2026 and about 71 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 97 trials still running at the 2026-10-09 snapshot; registered median of 22 months across 713 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Spondylarthropathies trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 44
Phase 1/2 8
Phase 2 106
Phase 2/3 15
Phase 3 189
Phase 4 119
Not applicable 222
Observational 436
Expanded access 2

How many Spondylarthropathies trials are recruiting? (11)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 59
Recruiting 133
Enrolling by invitation 8
Active, not recruiting 48
Available 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Spondylarthropathies trials? (13)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Novartis Pharmaceuticals 47
Pfizer 38
AbbVie 36
Amgen 23
Janssen Research & Development, LLC 23

Which drugs are being tested for Spondylarthropathies? (2)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
INFLIXIMAB 39
(CP-6890,550) Tofacitinib 18

Interventions as named in the registry (13)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Adalimumab-US 60
1=Etanercept 60
Secukinmab 56
HD- Methotrexate (MTX) 30
SC golimumab 28

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Spondylarthropathies trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 245 80
Osteoarthritis 224 68
Cholelithiasis 111 49
Atrial fibrillation 104 41
Myocardial infarction 99 45

Which publications cover Spondylarthropathies? (63)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (3)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

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