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Condition (MeSH)

Male Urogenital Diseases

ClinicalTrials.gov lists 28,325 trials for Male Urogenital Diseases or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 445.

MeSH D052801 Urogenital Diseases C12
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Phase 1 Phase 1 2,758 Phase 1/2 Phase 1/2 1,078 Phase 2 Phase 2 4,288 Phase 2/3 Phase 2/3 386 Phase 3 Phase 3 2,342 Phase 4 Phase 4 1,912 Not applicable Not applicable 8,588 Observational Observational 6,910 Phase 1 Phase 1 2,758 Phase 1/2 Phase 1/2 1,078 Phase 2 Phase 2 4,288 Phase 2/3 Phase 2/3 386 Phase 3 Phase 3 2,342 Phase 4 Phase 4 1,912 Not applicable Not applicable 8,588 Observational Observational 6,910

Trials per phase (log scale)

2 more sections with rows

34 of the 28,325 trials are tagged with Male Urogenital Diseases itself; the rest are tagged with a narrower condition beneath it.

Get the Male Urogenital Diseases report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Male Urogenital Diseases trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 60 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Expanded access, Unknown)

Top of scale: 1,710

1990: 11 trials (Observational 3, Not applicable 2, Phase 3 1, Phase 2 4, Phase 1/2 1) 1991: 8 trials (Observational 2, Phase 3 2, Phase 2 2, Phase 1 2) 1992: 17 trials (Observational 4, Phase 4 1, Phase 3 6, Phase 2 4, Phase 1 2) 1993: 19 trials (Observational 8, Not applicable 1, Phase 4 1, Phase 3 5, Phase 2/3 1, Phase 2 3) 1994: 26 trials (Observational 8, Phase 3 8, Phase 2/3 1, Phase 2 1, Phase 1/2 3, Phase 1 5) 1995: 42 trials (Observational 7, Not applicable 3, Phase 3 17, Phase 2/3 1, Phase 2 8, Phase 1/2 2, Phase 1 4) 1996: 48 trials (Observational 8, Not applicable 4, Phase 4 2, Phase 3 15, Phase 2 14, Phase 1/2 2, Phase 1 3) 1997: 77 trials (Observational 9, Not applicable 11, Phase 4 3, Phase 3 19, Phase 2 18, Phase 1/2 3, Phase 1 14) 1998: 103 trials (Observational 11, Not applicable 8, Phase 4 5, Phase 3 20, Phase 2/3 1, Phase 2 37, Phase 1/2 5, Phase 1 16) 1999: 118 trials (Observational 15, Not applicable 8, Phase 4 1, Phase 3 31, Phase 2/3 1, Phase 2 37, Phase 1/2 7, Phase 1 18) 2000: 171 trials (Observational 30, Not applicable 9, Phase 4 6, Phase 3 28, Phase 2/3 2, Phase 2 59, Phase 1/2 12, Phase 1 25) 2001: 212 trials (Observational 30, Not applicable 19, Phase 4 11, Phase 3 34, Phase 2/3 4, Phase 2 76, Phase 1/2 11, Phase 1 27) 2002: 262 trials (Observational 37, Not applicable 27, Phase 4 32, Phase 3 40, Phase 2/3 10, Phase 2 88, Phase 1/2 12, Phase 1 16) 2003: 383 trials (Observational 54, Not applicable 42, Phase 4 59, Phase 3 83, Phase 2/3 3, Phase 2 98, Phase 1/2 18, Phase 1 26) 2004: 481 trials (Observational 81, Not applicable 66, Phase 4 69, Phase 3 82, Phase 2/3 10, Phase 2 115, Phase 1/2 26, Phase 1 32) 2005: 603 trials (Other 1, Observational 94, Not applicable 112, Phase 4 83, Phase 3 81, Phase 2/3 9, Phase 2 138, Phase 1/2 35, Phase 1 50) 2006: 710 trials (Observational 115, Not applicable 115, Phase 4 74, Phase 3 92, Phase 2/3 16, Phase 2 180, Phase 1/2 44, Phase 1 74) 2007: 726 trials (Observational 141, Not applicable 124, Phase 4 63, Phase 3 97, Phase 2/3 22, Phase 2 179, Phase 1/2 16, Phase 1 84) 2008: 810 trials (Observational 189, Not applicable 152, Phase 4 84, Phase 3 87, Phase 2/3 14, Phase 2 167, Phase 1/2 24, Phase 1 93) 2009: 854 trials (Observational 190, Not applicable 169, Phase 4 104, Phase 3 107, Phase 2/3 20, Phase 2 142, Phase 1/2 32, Phase 1 90) 2010: 865 trials (Observational 220, Not applicable 160, Phase 4 81, Phase 3 91, Phase 2/3 17, Phase 2 157, Phase 1/2 38, Phase 1 101) 2011: 905 trials (Observational 225, Not applicable 200, Phase 4 89, Phase 3 86, Phase 2/3 16, Phase 2 151, Phase 1/2 29, Phase 1 109) 2012: 950 trials (Other 2, Observational 227, Not applicable 249, Phase 4 94, Phase 3 90, Phase 2/3 12, Phase 2 156, Phase 1/2 31, Phase 1 89) 2013: 1,000 trials (Other 2, Observational 237, Not applicable 291, Phase 4 88, Phase 3 79, Phase 2/3 13, Phase 2 149, Phase 1/2 39, Phase 1 102) 2014: 1,110 trials (Observational 270, Not applicable 362, Phase 4 73, Phase 3 80, Phase 2/3 12, Phase 2 156, Phase 1/2 46, Phase 1 111) 2015: 1,130 trials (Observational 271, Not applicable 356, Phase 4 95, Phase 3 86, Phase 2/3 14, Phase 2 137, Phase 1/2 42, Phase 1 129) 2016: 1,203 trials (Other 1, Observational 300, Not applicable 399, Phase 4 80, Phase 3 84, Phase 2/3 22, Phase 2 153, Phase 1/2 40, Phase 1 124) 2017: 1,256 trials (Observational 301, Not applicable 448, Phase 4 76, Phase 3 73, Phase 2/3 10, Phase 2 184, Phase 1/2 42, Phase 1 122) 2018: 1,312 trials (Observational 311, Not applicable 499, Phase 4 65, Phase 3 75, Phase 2/3 15, Phase 2 207, Phase 1/2 49, Phase 1 91) 2019: 1,421 trials (Observational 401, Not applicable 488, Phase 4 81, Phase 3 91, Phase 2/3 21, Phase 2 164, Phase 1/2 46, Phase 1 129) 2020: 1,344 trials (Other 1, Observational 412, Not applicable 444, Phase 4 56, Phase 3 82, Phase 2/3 10, Phase 2 168, Phase 1/2 37, Phase 1 134) 2021: 1,590 trials (Observational 468, Not applicable 546, Phase 4 65, Phase 3 98, Phase 2/3 19, Phase 2 183, Phase 1/2 62, Phase 1 149) 2022: 1,530 trials (Observational 437, Not applicable 593, Phase 4 60, Phase 3 86, Phase 2/3 11, Phase 2 156, Phase 1/2 50, Phase 1 137) 2023: 1,624 trials (Other 1, Observational 424, Not applicable 639, Phase 4 65, Phase 3 99, Phase 2/3 21, Phase 2 170, Phase 1/2 57, Phase 1 148) 2024: 1,710 trials (Observational 481, Not applicable 642, Phase 4 84, Phase 3 82, Phase 2/3 23, Phase 2 175, Phase 1/2 67, Phase 1 156) 2025: 1,707 trials (Observational 418, Not applicable 702, Phase 4 63, Phase 3 92, Phase 2/3 19, Phase 2 183, Phase 1/2 74, Phase 1 156)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1,699
2025 1,707
2024 1,710
2023 1,624
2022 1,530
2021 1,590
2020 1,344
2019 1,421
2018 1,312
2017 1,256

Forecast of the full-year count, planned starts included, not rows of this table: about 2,100 trials starting in 2026 and about 1,800 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 10 percent and ran about 4 percent high against the count later registered; forecasts made before the year began were off by about 25 percent and ran about 15 percent low against the count later registered, and had about 7 percent more error than repeating last year's count. The part-way figures are from forecasts that used a multiple fitted only on earlier years. A stricter check that trains only on older years did not support adding planned starts for conditions of this size: it ran about 6 percent high against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 2,747 trials still running at the 2026-10-09 snapshot; registered median of 25 months across 16,787 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Male Urogenital Diseases trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 2,758
Phase 1/2 1,078
Phase 2 4,288
Phase 2/3 386
Phase 3 2,342
Phase 4 1,912
Not applicable 8,588
Observational 6,910
Expanded access 60
Unknown 3

How many Male Urogenital Diseases trials are recruiting? (13)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1,339
Recruiting 3,531
Enrolling by invitation 210
Active, not recruiting 1,431
Available 14

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Male Urogenital Diseases trials? (7)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 445
Bayer 227
Pfizer 216
AstraZeneca 197
Novartis Pharmaceuticals 192

Which drugs are being tested for Male Urogenital Diseases? (8)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Prednisone 268
PEMBROLIZUMAB 229
Abiraterone 215
Enzalutamide 197
NIVOLUMAB 187

Interventions as named in the registry (7)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Docetetaxel 309
Gemcitabine/Gemzar 189
Sunitinib 4/2 160
Radiation Therapy 151
Cisplatin 1 150

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Male Urogenital Diseases trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 7,778 767
Major Adverse Cardiovascular Events 6,762 1
Major Adverse Kidney Events 5,557 1
Sepsis 3,673 651
Urinary tract infection 3,624 556

Which publications cover Male Urogenital Diseases? (41)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (6)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages