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Condition (MeSH)

Chronic Periodontitis

ClinicalTrials.gov lists 355 trials for Chronic Periodontitis or a narrower condition beneath it.

MeSH D055113 Stomatognathic Diseases C07 C23
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Phase 1 Phase 1 12 Phase 1/2 Phase 1/2 10 Phase 2 Phase 2 26 Phase 2/3 Phase 2/3 25 Phase 3 Phase 3 16 Phase 4 Phase 4 50 Not applicable Not applicable 153 Observational Observational 63 Phase 1 Phase 1 12 Phase 1/2 Phase 1/2 10 Phase 2 Phase 2 26 Phase 2/3 Phase 2/3 25 Phase 3 Phase 3 16 Phase 4 Phase 4 50 Not applicable Not applicable 153 Observational Observational 63

Trials per phase

355 of the 355 trials are tagged with Chronic Periodontitis itself; the rest are tagged with a narrower condition beneath it.

Get the Chronic Periodontitis report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Chronic Periodontitis trials start? (24)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 45

1999: 1 trials (Phase 3 1) 2002: 1 trials (Not applicable 1) 2004: 2 trials (Phase 3 1, Phase 1/2 1) 2006: 7 trials (Not applicable 2, Phase 4 2, Phase 3 2, Phase 2 1) 2007: 2 trials (Phase 4 2) 2008: 5 trials (Observational 1, Not applicable 3, Phase 4 1) 2009: 4 trials (Phase 4 1, Phase 3 1, Phase 2 1, Phase 1 1) 2010: 12 trials (Observational 2, Not applicable 3, Phase 4 5, Phase 2/3 1, Phase 1/2 1) 2011: 14 trials (Observational 2, Not applicable 7, Phase 4 4, Phase 2 1) 2012: 18 trials (Observational 2, Not applicable 8, Phase 4 3, Phase 3 2, Phase 2 2, Phase 1 1) 2013: 31 trials (Observational 5, Not applicable 12, Phase 4 4, Phase 3 1, Phase 2/3 4, Phase 2 4, Phase 1 1) 2014: 45 trials (Observational 4, Not applicable 22, Phase 4 4, Phase 3 2, Phase 2/3 8, Phase 2 4, Phase 1/2 1) 2015: 42 trials (Observational 12, Not applicable 10, Phase 4 6, Phase 3 3, Phase 2/3 6, Phase 2 4, Phase 1/2 1) 2016: 28 trials (Observational 4, Not applicable 14, Phase 4 4, Phase 2/3 3, Phase 1/2 1, Phase 1 2) 2017: 25 trials (Observational 7, Not applicable 14, Phase 2 2, Phase 1/2 2) 2018: 26 trials (Observational 5, Not applicable 11, Phase 4 4, Phase 2/3 2, Phase 2 1, Phase 1/2 1, Phase 1 2) 2019: 17 trials (Observational 2, Not applicable 9, Phase 4 3, Phase 2 2, Phase 1 1) 2020: 15 trials (Not applicable 5, Phase 4 4, Phase 2/3 1, Phase 2 1, Phase 1/2 2, Phase 1 2) 2021: 12 trials (Observational 4, Not applicable 4, Phase 4 1, Phase 3 1, Phase 2 2) 2022: 12 trials (Observational 3, Not applicable 8, Phase 1 1) 2023: 10 trials (Observational 3, Not applicable 5, Phase 3 2) 2024: 13 trials (Observational 5, Not applicable 6, Phase 2 1, Phase 1 1) 2025: 7 trials (Not applicable 6, Phase 4 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 6
2025 7
2024 13
2023 10
2022 12
2021 12
2020 15
2019 17
2018 26
2017 25

Forecast of the full-year count, planned starts included, not rows of this table: about 8 trials starting in 2026 and about 9 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 30 months from start to primary completion across 11 trials still running at the 2026-10-09 snapshot; registered median of 12 months across 282 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Chronic Periodontitis trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 12
Phase 1/2 10
Phase 2 26
Phase 2/3 25
Phase 3 16
Phase 4 50
Not applicable 153
Observational 63

How many Chronic Periodontitis trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 5
Recruiting 10
Active, not recruiting 5
Completed 266
Terminated 9

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which drugs are being tested for Chronic Periodontitis? (4)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Platelet Rich Fibrin 6
ROSUVASTATIN 4
Amoxicillin 4
Aloe Vera Gel 3

Interventions as named in the registry (11)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
open flap debridement 14
(PDT) Photodynamic therapy 6
Metronidazol 5
SRP 4
2% chlorhexidine 3

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Chronic Periodontitis trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Abdominal hernia 1 1
Back pain 1 1
Brain neoplasm 1 1
Cast 1 1
Cellulitis and pulmonary embolism 1 1

Which publications cover Chronic Periodontitis? (387)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, prevalence, rare-disease identity, and sub-conditions in mesh.

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