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Condition (MeSH)

Rickets, Hypophosphatemic

ClinicalTrials.gov lists 53 trials for Rickets, Hypophosphatemic or a narrower condition beneath it. Kyowa Kirin Co., Ltd. has the most among industry and government lead sponsors, with 10.

MeSH D063730 Musculoskeletal Diseases C05 C18
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Phase 1 Phase 1 6 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 3 Phase 3 Phase 3 9 Phase 4 Phase 4 5 Not applicable Not applicable 6 Observational Observational 18 Expanded access Expanded access 1 Phase 1 Phase 1 6 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 3 Phase 3 Phase 3 9 Phase 4 Phase 4 5 Not applicable Not applicable 6 Observational Observational 18 Expanded access Expanded access 1

Trials per phase

9 of the 53 trials are tagged with Rickets, Hypophosphatemic itself; the rest are tagged with a narrower condition beneath it.

Get the Rickets, Hypophosphatemic report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Rickets, Hypophosphatemic trials start? (20)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 7

2004: 1 trials (Phase 1 1) 2005: 1 trials (Phase 1 1) 2006: 1 trials (Phase 1/2 1) 2007: 1 trials (Phase 3 1) 2008: 1 trials (Phase 1 1) 2009: 1 trials (Not applicable 1) 2011: 3 trials (Not applicable 2, Phase 1/2 1) 2012: 2 trials (Phase 1/2 1, Phase 1 1) 2014: 2 trials (Phase 2 1, Phase 1 1) 2015: 4 trials (Not applicable 1, Phase 3 2, Phase 2 1) 2016: 2 trials (Phase 3 1, Phase 2 1) 2017: 3 trials (Observational 1, Phase 4 1, Phase 3 1) 2018: 6 trials (Observational 4, Phase 4 1, Phase 3 1) 2019: 6 trials (Observational 3, Phase 4 1, Phase 3 1, Phase 1 1) 2020: 4 trials (Observational 3, Phase 1/2 1) 2021: 7 trials (Observational 3, Phase 4 2, Phase 3 2) 2022: 1 trials (Observational 1) 2024: 2 trials (Observational 1, Phase 1/2 1) 2025: 2 trials (Observational 1, Not applicable 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 2
2025 2
2024 2
2022 1
2021 7
2020 4
2019 6
2018 6
2017 3
2016 2

No forecast is made for this condition: it averages 1.8 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 2 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Rickets, Hypophosphatemic trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 6
Phase 1/2 5
Phase 2 3
Phase 3 9
Phase 4 5
Not applicable 6
Observational 18
Expanded access 1

How many Rickets, Hypophosphatemic trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 1
Recruiting 4
Active, not recruiting 4
Available 1
Completed 34

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Rickets, Hypophosphatemic trials? (6)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Kyowa Kirin Co., Ltd. 10
Kyowa Kirin, Inc. 6
Kyowa Kirin Pharmaceutical Development Ltd 5
Medialis Ltd. 1
National Institute of Dental and Craniofacial Research (NIDCR) 1

Which drugs are being tested for Rickets, Hypophosphatemic? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Burosumab 20
Calcitriol 2
Cinacalcet 2

Interventions as named in the registry (12)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
NaCl 0.9% NS 1
Burosumab Injection [Crysvita] 1
Oral Magnesium Supplement 1
No treatment given 1
Active vitamin D 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Rickets, Hypophosphatemic trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Arthralgia 4 1
Craniosynostosis 4 1
Migraine 4 2
Myelopathy 4 1
Cervical Spinal Stenosis 3 2

Prevalence (2)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Hypophosphatemic rickets Point prevalence Unknown Worldwide Not stated Exact
Hypophosphatemic rickets Point prevalence Unknown Worldwide Not stated Exact

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Hypophosphatemic rickets 437 Exact Orphanet Rare Disease Ontology (ORDO)
Hypophosphatemic rickets 437 Exact Orphadata Science knowledge files, Product 1

Sub-conditions in MeSH (1)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: publications.

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