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Organization (Academic)

University of Waterloo

ClinicalTrials.gov lists University of Waterloo as lead sponsor of 90 trials. It has 2 active development programs and 14 approved assets.

CA Academic
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14 0 1995 2027

Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.

2026 is partial: 11 registered with a 2026 start date. The hollow diamonds on the dashed line are a forecast of the full-year count, planned starts included: about 12 in 2026 and about 8 in 2027, the average of the 24 months through September, counted as registered and carried forward. The columns, the lighter one included, count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. This method has not been backtested on organizations. In backtests on conditions with as many trial starts a year as this organization (5 to 20), forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Logo University of Waterloo, via Wikimedia Commons, Public domain. Shown to identify the organization; it may be a registered trademark.

This page covers University of Waterloo: 90 lead-sponsored trials and 1 legal-entity registration.

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Disease areas (69)

Shown in this order: most trials first.

Disease areas
Disease area Trials
Myopia 19
Dry Eye Syndromes 18
Bone Diseases, Metabolic 9
Osteoporosis 9
Vision Disorders 7

Trials by start year as sponsor or collaborator (23)

Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Show the table of trials by start year as sponsor or collaborator
Trials by start year as sponsor or collaborator
Year Trials started
2026 (partial year) 11
2025 6
2024 5
2023 13
2022 8
2021 8
2020 4
2019 14
2018 9
2017 7

Recruitment duration, a model prediction: 4 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

Active development programs (2)

Shown in this order: max phase, then active trials.

Active development programs
Drug Disease area Max phase Trials
EXERCISE TRAINING WITH OR WITHOUT MEDICATION Insulin Resistance Not reported 1
0.09% cyclosporine A ophthalmic solution Dry Eye Syndromes Not reported 1

Approved assets (14)

Shown in this order: max phase first.

Approved assets
Drug Trials
Soft contact lens multipurpose disinfection regimen 1
TheraTears® Lubricant Eye Drop 1
Marketed multipurpose disinfection regimen 1
Optifree RepleniSH Multipurpose Disinfecting Solution 1
Methazolamide Pill 1

Sponsor delivery record (1)

Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.

Sponsor delivery record
Enrollment Timeline
47% hit target (n=38) 35% on time (n=37)

Journals published in (156)

Shown in this order: most published in first.

Journals published in
Journal Publications
American journal of respiratory and critical care medicine 11
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 8
JAMA 7
The European respiratory journal 7
The Cochrane database of systematic reviews 6

US granted patents (1)

Patents are not classified by disease area in the source, so this is the organization's overall portfolio, not a split by disease.

US granted patents
US patents granted Granted in the last 5 years Most recent grant
129 8 2025-12-16

Financing and grant events (5)

Shown in this order: most recent first.

Financing and grant events
Date Round type Amount (USD) Source
2025-09-18 NIH grant 170,362 Reporter
2025-08-11 NIH grant 314,576 Reporter
2024-06-10 NIH grant 331,230 Reporter
2024-06-10 NIH grant 191,233 Reporter
2020-05-19 NIH grant 190,168 Reporter

Organization relationships (18)

Shown in this order: most evidence first.

Organization relationships
Related organization Relationship Evidence
Radboud University Medical Center Co sponsors trial with 2
Sjögren’s Society of Canada Co sponsors trial with 1
The University of Sydney Co sponsors trial with 1
Emory University Co sponsors trial with 1
University of Rome Tor Vergata Co sponsors trial with 1

Latest dated events (281)

Shown in this order: newest first.

Latest dated events
Date Event Source
2026-11-01 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))
2026-09-01 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))
2026-08-15 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))
2026-08 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))
2026-07-01 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))

Biomarker capability evidence (36)

Shown in this order: tier desc, then gene symbol.

Biomarker capability evidence
Gene Role Evidence
ACADSB Testing lab / CRO (runs the assay) Clinical-testing interpretation submitted (ClinVar)
FRAS1 Testing lab / CRO (runs the assay) Clinical-testing interpretation submitted (ClinVar)
GCNT2 Testing lab / CRO (runs the assay) Clinical-testing interpretation submitted (ClinVar)
GNAQ Trial sponsor Named in trial inclusion criteria
HFE Testing lab / CRO (runs the assay) Clinical-testing interpretation submitted (ClinVar)

Biomarkers this organization publishes on (287)

Shown in this order: most publications first.

Biomarkers this organization publishes on
Biomarker Publications
INS 13
CRP 7
IL6 7
ALB 5
IGF1 5

On Scientist.com

University of Waterloo is listed as a research supplier in the Scientist.com network.

THE UNIVERSITY OF WATERLOO CENTRAL ANIMAL FACILITY OFFERS YOU A NEW AND STATE-OF-THE-ART FACILITY: Certificate of Good Animal Practice from the Canadian Council on Animal Care in Science and licensed by the Ontario Ministry of Agriculture, Food, and Rural Affairs (OMAFRA) » Certified and experienced animal health technicians, i.e., Registered Laboratory Animal Technicians (RLAT), Registered Master Animal Technician (RMLAT), Certified Manager Animal Resources (CMAR) and licensed veterinarian » Ability to house rodents (e.g., mice, rats, guinea pigs, gerbils) and rabbits; other animal species...

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THE UNIVERSITY OF WATERLOO CENTRAL ANIMAL FACILITY OFFERS YOU A NEW AND STATE-OF-THE-ART FACILITY: Certificate of Good Animal Practice from the Canadian Council on Animal Care in Science and licensed by the Ontario Ministry of Agriculture, Food, and Rural Affairs (OMAFRA)

» Certified and experienced animal health technicians, i.e., Registered Laboratory Animal Technicians (RLAT), Registered Master Animal Technician (RMLAT), Certified Manager Animal Resources (CMAR) and licensed veterinarian
» Ability to house rodents (e.g., mice, rats, guinea pigs, gerbils) and rabbits; other animal species (e.g., geckos, lizards, snakes) also possible
» Chemistry lab
» Observation/recording room
» Restricted access mouse suite
» ABSL2 housing and procedural space
» Necropsy room
» Surgical suite with waste gas scavenging units and anesthetic machines
» Surgical recovery room
» Quarantine room
» Dedicated behavioural research room
» Fully equipped conference/training room with digital projection unit
» Change rooms and showers Maintenance of rodent breeding colonies and tissue sample collection for genotyping
» Technical expertise with drug administration, sample collection, and simple surgeries, e.g., device implants
» Tumour cell line inoculations and tumour measurements
» Surgical and anesthetic assistance, including preparation of surgical packs
» Polyclonal and monoclonal antibody production
» C-section and fostering of rodent lines
» Health screening and monitoring for serology, bacteriology, parasitology, and cell line testing
» Necropsy and perfusion

Website
uwaterloo.ca

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