Organization (Industry)
G1 Therapeutics (United States)
ClinicalTrials.gov lists G1 Therapeutics (United States) as lead sponsor of 16 trials. It has 56 active development programs and 17 approved assets.
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Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 0 registered with a 2026 start date. The dashed outline is the pace from the 0 registered with a start date through September, planned starts included, not adjusted; not a forecast. No forecast is made for this organization: it averages 0.8 trial starts a year over the five years to September, under the 5 a year the method needs.
This page covers G1 Therapeutics (United States): 16 lead-sponsored trials and 1 legal-entity registration.
Disease areas (11)
Shown in this order: most trials first.
| Disease area | Trials |
|---|---|
| Lung Neoplasms | 10 |
| Small Cell Lung Carcinoma | 8 |
| Breast Neoplasms | 7 |
| Triple Negative Breast Neoplasms | 5 |
| Neoplasm Metastasis | 4 |
Showing 5 of 11 disease areas.
Trials by start year as sponsor or collaborator (9)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2024 | 1 |
| 2022 | 2 |
| 2021 | 7 |
| 2020 | 1 |
| 2018 | 2 |
| 2017 | 3 |
| 2016 | 1 |
| 2015 | 2 |
| 2014 | 1 |
Recruitment duration, a model prediction: none of the 16 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Active development programs (56)
Shown in this order: max phase, then active trials.
| Drug | Disease area | Max phase | Trials |
|---|---|---|---|
| Trilaciclib | Triple Negative Breast Neoplasms | Phase 3 | 4 |
| Trilaciclib | Breast Neoplasms | Phase 3 | 4 |
| Trilaciclib | Neoplasm Metastasis | Phase 3 | 3 |
| CARBOPLATIN | Triple Negative Breast Neoplasms | Phase 3 | 3 |
| CARBOPLATIN | Breast Neoplasms | Phase 3 | 3 |
Showing 5 of 56 active programs.
Approved assets (17)
Shown in this order: max phase first.
| Drug | Trials |
|---|---|
| Trilaciclib | 11 |
| CARBOPLATIN | 6 |
| GEMCITABINE | 3 |
| ETOPOSIDE | 2 |
| ATEZOLIZUMAB | 1 |
Showing 5 of 17 approved assets.
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 56% hit target (n=9) | 45% on time (n=11) |
Journals published in (17)
Shown in this order: most published in first.
| Journal | Publications |
|---|---|
| Advances in therapy | 1 |
| Annals of oncology : official journal of the European Society for Medical Oncology | 1 |
| Breast cancer research and treatment | 1 |
| Cancer chemotherapy and pharmacology | 1 |
| Cancer management and research | 1 |
Showing 5 of 17 journals.
US granted patents (1)
Patents are not classified by disease area in the source, so this is the organization's overall portfolio, not a split by disease.
| US patents granted | Granted in the last 5 years | Most recent grant |
|---|---|---|
| 48 | 12 | 2024-12-17 |
FDA inspection record (1)
| Latest classification | Inspections |
|---|---|
| NAI | 1 |
Organization relationships (4)
Shown in this order: most evidence first.
| Related organization | Relationship | Evidence |
|---|---|---|
| Jiangsu Simcere Pharmaceutical Co., Ltd. | Co sponsors trial with | 2 |
| Roche (Switzerland) | Co sponsors trial with | 1 |
| Bionical Emas | Co sponsors trial with | 1 |
| Roche-Genentech | Co sponsors trial with | 1 |
Latest dated events (69)
Shown in this order: newest first.
| Date | Event | Source |
|---|---|---|
| 2024-12-17 | Patent granted | Granted US patents (PatentsView / USPTO) |
| 2024-11-12 | Patent granted | Granted US patents (PatentsView / USPTO) |
| 2024-01-10 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2023-12-07 | FDA inspection | FDA enforcement (warning and untitled letters, recalls, inspections, import refusals, debarment) |
| 2023-08-08 | Patent granted | Granted US patents (PatentsView / USPTO) |
Showing 5 of 69 events.
Biomarker capability evidence (106)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| ALB | Trial collaborator | Named in trial inclusion criteria |
| ALK | Trial sponsor | Named in trial inclusion criteria |
| BRAF | Trial sponsor | Named in trial inclusion criteria |
| CD274 | Trial collaborator | Named in trial inclusion criteria |
| CD274 | Trial collaborator | Named in trial inclusion criteria |
Showing 5 of 106 evidence rows.
Not on this page
Checked, with nothing recorded for this organization: companies grouped under this page, related companies not grouped here, sec-reported annual financials, financing and grant events, fda warning letters, fda untitled letters, fda recalls, fda import refusals, manufacturing and distribution sites, climate targets, as filed, workforce and board diversity, as filed, clia clinical laboratory certificates, and biomarkers this organization publishes on.