Organization (Academic)
University of Cape Town
ClinicalTrials.gov lists University of Cape Town as lead sponsor of 116 trials. It has 18 active development programs and 30 approved assets.
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Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 9 registered with a 2026 start date. The hollow diamonds on the dashed line are a forecast of the full-year count, planned starts included: about 11 in 2026 and about 9 in 2027, the average of the 24 months through September, counted as registered and carried forward. The columns, the lighter one included, count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. This method has not been backtested on organizations. In backtests on conditions with as many trial starts a year as this organization (5 to 20), forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored. 1 trial is registered to start in 2027 or later.
This page covers University of Cape Town: 116 lead-sponsored trials and 1 legal-entity registration.
Disease areas (156)
Shown in this order: most trials first.
| Disease area | Trials |
|---|---|
| Tuberculosis | 61 |
| HIV Infections | 49 |
| Acquired Immunodeficiency Syndrome | 29 |
| Malaria | 11 |
| COVID-19 | 9 |
Showing 5 of 156 disease areas.
Trials by start year as sponsor or collaborator (28)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2026 (partial year) | 9 |
| 2025 | 8 |
| 2024 | 10 |
| 2023 | 17 |
| 2022 | 22 |
| 2021 | 17 |
| 2020 | 15 |
| 2019 | 28 |
| 2018 | 19 |
| 2017 | 12 |
Showing 10 of 28 years.
Prediction, not a registry value: median of 36 months from start to primary completion across 10 trials still running at the 2026-10-09 snapshot; registered median of 19 months across 76 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Active development programs (18)
Shown in this order: max phase, then active trials.
| Drug | Disease area | Max phase | Trials |
|---|---|---|---|
| Atorvastatin 40mg | Pulmonary Disease, Chronic Obstructive | Phase 2/3 | 1 |
| Atorvastatin 40mg | Tuberculosis, Pulmonary | Phase 2/3 | 1 |
| Atorvastatin 40mg | Tuberculosis | Phase 2/3 | 1 |
| Atorvastatin 40mg | Inflammation | Phase 2/3 | 1 |
| Dolutegravir 50 MG | HIV Infections | Phase 2 | 2 |
Showing 5 of 18 active programs.
Approved assets (30)
Shown in this order: max phase first.
| Drug | Trials |
|---|---|
| Artemether + Lumefantrine | 3 |
| Lopinavir / Ritonavir | 1 |
| 8 hourly LPV/r during TB treatment | 1 |
| Diclofenac 50 mg tds | 1 |
| Etoricoxib 120 mg mane | 1 |
Showing 5 of 30 approved assets.
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 61% hit target (n=33) | 22% on time (n=32) |
Journals published in (361)
Shown in this order: most published in first.
| Journal | Publications |
|---|---|
| Antimicrobial agents and chemotherapy | 39 |
| Lancet (London, England) | 34 |
| The New England journal of medicine | 34 |
| AIDS (London, England) | 30 |
| Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 28 |
Showing 5 of 361 journals.
US granted patents (1)
Patents are not classified by disease area in the source, so this is the organization's overall portfolio, not a split by disease.
| US patents granted | Granted in the last 5 years | Most recent grant |
|---|---|---|
| 95 | 26 | 2025-12-02 |
Financing and grant events (182)
Shown in this order: most recent first.
| Date | Round type | Amount (USD) | Source |
|---|---|---|---|
| 2025-09-22 | NIH grant | 614,534 | Reporter |
| 2025-09-15 | NIH grant | 952,640 | Reporter |
| 2025-09-11 | NIH grant | 308,214 | Reporter |
| 2025-09-04 | NIH grant | 587,434 | Reporter |
| 2025-08-26 | NIH grant | 199,994 | Reporter |
Showing 5 of 182 events.
Organization relationships (154)
Shown in this order: most evidence first.
| Related organization | Relationship | Evidence |
|---|---|---|
| Government of the United States of America | Co sponsors trial with | 23 |
| Stellenbosch University | Co sponsors trial with | 14 |
| South African Medical Research Council | Co sponsors trial with | 11 |
| University of California System | Co sponsors trial with | 8 |
| University of Oxford | Co sponsors trial with | 8 |
Showing 5 of 154 relationships.
Latest dated events (548)
Shown in this order: newest first.
| Date | Event | Source |
|---|---|---|
| 2027-02-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-09-15 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-07-08 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-06-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-05-20 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
Showing 5 of 548 events.
Biomarker capability evidence (255)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| ADA | Trial sponsor | Named in trial inclusion criteria |
| ART5 | Trial collaborator | Named in trial inclusion criteria |
| BLVRB | Trial sponsor | Named in trial inclusion criteria |
| CCL20 | Trial collaborator | Named in trial inclusion criteria |
| CD4 | Trial sponsor | Named in trial inclusion criteria |
Showing 5 of 255 evidence rows.
Biomarkers this organization publishes on (840)
Shown in this order: most publications first.
Showing 5 of 840 biomarkers.
Not on this page
Checked, with nothing recorded for this organization: companies grouped under this page, related companies not grouped here, sec-reported annual financials, fda warning letters, fda untitled letters, fda inspection record, fda recalls, fda import refusals, manufacturing and distribution sites, climate targets, as filed, workforce and board diversity, as filed, and clia clinical laboratory certificates.