Clinical trial
A Phase 1B/II Study of GDC-0449 (NSC 747691) in Combination With RO4929097, a Gamma-Secretase Inhibitor (GSI) in Advanced/Metastatic Sarcomas
NCT01154452 is registered in ClinicalTrials.gov with National Cancer Institute (NCI) as lead sponsor.
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Registry record
As filed in ClinicalTrials.gov.
- Title
- A Phase 1B/II Study of GDC-0449 (NSC 747691) in Combination With RO4929097, a Gamma-Secretase Inhibitor (GSI) in Advanced/Metastatic Sarcomas
- Lead sponsor
- National Cancer Institute (NCI)
- Phase
- Phase 1/2
- Overall status
- Completed
- Start date
- June 30, 2010
- Completion date
- February 28, 2015
- Enrollment
- 78 (actual)
- Sites
- 1
Conditions
As the registry lists them; a condition with its own page is linked.
adult alveolar soft part sarcoma, adult angiosarcoma, adult desmoplastic small round cell tumor, adult epithelioid hemangioendothelioma, adult epithelioid sarcoma, adult extraskeletal myxoid chondrosarcoma, adult extraskeletal osteosarcoma, adult fibrosarcoma, adult leiomyosarcoma, adult liposarcoma, adult malignant mesenchymoma, adult malignant peripheral nerve sheath tumor, adult rhabdomyosarcoma, adult synovial sarcoma, adult unclassified pleomorphic sarcoma, chondrosarcoma, clear cell sarcoma of the kidney, conjunctival kaposi sarcoma, dermatofibrosarcoma protuberans, gastrointestinal stromal tumor, metastatic ewing sarcoma/peripheral primitive neuroectodermal tumor, metastatic osteosarcoma, ovarian sarcoma, recurrent adult soft tissue sarcoma, recurrent adult unclassified pleomorphic sarcoma of bone, recurrent ewing sarcoma/peripheral primitive neuroectodermal tumor, recurrent kaposi sarcoma, recurrent osteosarcoma, recurrent uterine corpus sarcoma, small intestine leiomyosarcoma, stage iii adult soft tissue sarcoma, stage iii uterine sarcoma, stage iv adult soft tissue sarcoma, stage iv uterine sarcoma, unclassified pleomorphic sarcoma of bone