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Clinical trial

A Phase I/II Study of Azacitidine, Venetoclax and Pevonedistat in Adults With Newly Diagnosed Secondary or Therapy-Related AML

NCT03862157 is registered in ClinicalTrials.gov with M.D. Anderson Cancer Center as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase I/II Study of Azacitidine, Venetoclax and Pevonedistat in Adults With Newly Diagnosed Secondary or Therapy-Related AML
Lead sponsor
M.D. Anderson Cancer Center
Phase
Phase 1/2
Overall status
Active, not recruiting
Start date
February 27, 2019
Completion date
January 31, 2027
Enrollment
40 (actual)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

acute myeloid leukemia, atypical chronic myeloid leukemia, bcr-abl1 negative, chronic eosinophilic leukemia, not otherwise specified, chronic myelomonocytic leukemia, chronic neutrophilic leukemia, essential thrombocythemia, myelodysplastic syndrome, myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis, myelodysplastic/myeloproliferative neoplasm, unclassifiable, myeloid neoplasm, myeloproliferative neoplasm, myeloproliferative neoplasm, unclassifiable, overt primary myelofibrosis, polycythemia vera, polycythemia vera, post-polycythemic myelofibrosis phase, prefibrotic/early primary myelofibrosis