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Clinical trial

A First-in-human Phase I Single-agent Dose-escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

NCT04541082 is registered in ClinicalTrials.gov with Jazz Pharmaceuticals as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A First-in-human Phase I Single-agent Dose-escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
Lead sponsor
Jazz Pharmaceuticals
Phase
Phase 1
Overall status
Recruiting
Start date
October 26, 2020
Completion date
December 31, 2026
Enrollment
102 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

anaplastic astrocytoma, anaplastic meningioma, anaplastic oligodendroglioma, anaplastic pleomorphic xanthoastrocytoma, atypical meningioma, central nervous system neoplasms, choroid plexus neoplasms, diffuse astrocytoma, diffuse midline glioma, h3 k27m-mutant, ependymoma, ependymoma, anaplastic, glial tumor, glioblastoma, gliomatosis cerebri, gliosarcoma, adult, medulloblastoma, neuroectodermal tumors, neuroectodermal tumors, primitive, oligodendroglioma, pilocytic astrocytoma, pineal tumor, pleomorphic xanthoastrocytoma, teratoid rhabdoid tumor