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Clinical trial

Phase 1/1b Study of AKT Inhibitor Ipatasertib With Chemoradiation for Locally Advanced Head and Neck Cancer

NCT05172245 is registered in ClinicalTrials.gov with National Cancer Institute (NCI) as lead sponsor.

NCT NCT05172245
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Registry record

As filed in ClinicalTrials.gov.

Title
Phase 1/1b Study of AKT Inhibitor Ipatasertib With Chemoradiation for Locally Advanced Head and Neck Cancer
Lead sponsor
National Cancer Institute (NCI)
Phase
Phase 1
Overall status
Recruiting
Start date
September 19, 2022
Completion date
July 1, 2027
Enrollment
46 (estimated)
Sites
18

Conditions

As the registry lists them; a condition with its own page is linked.

clinical stage ii hpv-mediated (p16-positive) oropharyngeal carcinoma ajcc v8, clinical stage iii hpv-mediated (p16-positive) oropharyngeal carcinoma ajcc v8, head and neck carcinoma of unknown primary, locally advanced head and neck squamous cell carcinoma, locally advanced hypopharyngeal squamous cell carcinoma, locally advanced laryngeal squamous cell carcinoma, locally advanced nasal cavity squamous cell carcinoma, locally advanced oral cavity squamous cell carcinoma, locally advanced oropharyngeal squamous cell carcinoma, locally advanced paranasal sinus squamous cell carcinoma, locally advanced sinonasal squamous cell carcinoma, maxillary sinus squamous cell carcinoma, stage iii hypopharyngeal carcinoma ajcc v8, stage iii laryngeal cancer ajcc v8, stage iii lip and oral cavity cancer ajcc v8, stage iii oropharyngeal (p16-negative) carcinoma ajcc v8, stage iii sinonasal cancer ajcc v8, stage iva hypopharyngeal carcinoma ajcc v8, stage iva laryngeal cancer ajcc v8, stage iva lip and oral cavity cancer ajcc v8, stage iva oropharyngeal (p16-negative) carcinoma ajcc v8, stage iva sinonasal cancer ajcc v8, stage ivb hypopharyngeal carcinoma ajcc v8, stage ivb laryngeal cancer ajcc v8, stage ivb lip and oral cavity cancer ajcc v8, stage ivb oropharyngeal (p16-negative) carcinoma ajcc v8, stage ivb sinonasal cancer ajcc v8