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Clinical trial

A Phase I Study to Investigate the Safety, Tolerability, and Preliminary Efficacy of Anti-CD30 Bispecific Antibody-Armed Anti-CD3-Activated Autologous T-Cells (CD30 biAb-AATC) in Patients With Relapsed/Refractory CD30 Positive Hematopoietic Malignancies

NCT05544968 is registered in ClinicalTrials.gov with Medical College of Wisconsin as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase I Study to Investigate the Safety, Tolerability, and Preliminary Efficacy of Anti-CD30 Bispecific Antibody-Armed Anti-CD3-Activated Autologous T-Cells (CD30 biAb-AATC) in Patients With Relapsed/Refractory CD30 Positive Hematopoietic Malignancies
Lead sponsor
Medical College of Wisconsin
Phase
Phase 1
Overall status
Recruiting
Start date
March 4, 2026
Completion date
July 31, 2029
Enrollment
42 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

cd30+ anaplastic large cell lymphoma, cd30+ immunoblastic large t-cell cutaneous lymphoma, cd30+ pleomorphic large t-cell cutaneous lymphoma, cd30-positive diffuse large b-cell lymphoma, hodgkin disease, leukemia, lymphoma