Clinical trial
DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial): An Umbrella-Basket Platform Trial to Evaluate the Efficacy of Targeted Therapies in Rare Adult, Paediatric and Teenage/Young Adult (TYA) Cancers With Actionable Genomic Alterations, Including Common Cancers With Rare Actionable Alterations. Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers
NCT05770037 is registered in ClinicalTrials.gov with Cancer Research UK as lead sponsor.
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Registry record
As filed in ClinicalTrials.gov.
- Title
- DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial): An Umbrella-Basket Platform Trial to Evaluate the Efficacy of Targeted Therapies in Rare Adult, Paediatric and Teenage/Young Adult (TYA) Cancers With Actionable Genomic Alterations, Including Common Cancers With Rare Actionable Alterations. Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers
- Lead sponsor
- Cancer Research UK
- Phase
- Phase 2/3
- Overall status
- Recruiting
- Start date
- December 18, 2023
- Completion date
- October 31, 2029
- Enrollment
- 30 (estimated)
- Sites
- 27
Conditions
As the registry lists them; a condition with its own page is linked.
anaplastic large cell lymphoma, cancer, haematological malignancy, lymphoma, lymphoproliferative disorders, malignant neoplasm, neoplasms by histologic type, neoplasms by site, neuroblastoma, renal cell carcinoma, solid tumour