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Clinical trial

AFFORD IO: A Phase 2 Trial of Low Dose, Reduced Frequency Nivolumab (Anti-PD-1 Antibody) in Patients With Unresectable or Metastatic Cancer

NCT07576725 is registered in ClinicalTrials.gov with Fred Hutchinson Cancer Center as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
AFFORD IO: A Phase 2 Trial of Low Dose, Reduced Frequency Nivolumab (Anti-PD-1 Antibody) in Patients With Unresectable or Metastatic Cancer
Lead sponsor
Fred Hutchinson Cancer Center
Phase
Phase 2
Overall status
Not yet recruiting
Start date
December 1, 2026
Completion date
August 31, 2029
Enrollment
50 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

clinical stage iii cutaneous melanoma ajcc v8, clinical stage iii cutaneous merkel cell carcinoma ajcc v8, clinical stage iv cutaneous melanoma ajcc v8, clinical stage iv cutaneous merkel cell carcinoma ajcc v8, hodgkin lymphoma, kaposi sarcoma, metastatic acral lentiginous melanoma, metastatic basal cell carcinoma, metastatic cervical carcinoma, metastatic clear cell renal cell carcinoma, metastatic colorectal carcinoma, metastatic cutaneous melanoma, metastatic head and neck squamous cell carcinoma, metastatic kaposi sarcoma, metastatic lung non-small cell carcinoma, metastatic malignant solid neoplasm, metastatic merkel cell carcinoma, metastatic mucosal melanoma, metastatic skin squamous cell carcinoma, metastatic urothelial carcinoma, stage iii cervical cancer ajcc v8, stage iii colorectal cancer ajcc v8, stage iii head and neck cutaneous squamous cell carcinoma ajcc v8, stage iii lung cancer ajcc v8, stage iii renal cell cancer ajcc v8, stage iv cervical cancer ajcc v8, stage iv colorectal cancer ajcc v8, stage iv head and neck cutaneous squamous cell carcinoma ajcc v8, stage iv lung cancer ajcc v8, stage iv renal cell cancer ajcc v8, unresectable acral lentiginous melanoma, unresectable basal cell carcinoma, unresectable cervical carcinoma, unresectable clear cell renal cell carcinoma, unresectable colorectal carcinoma, unresectable cutaneous melanoma, unresectable head and neck squamous cell carcinoma, unresectable lung non-small cell carcinoma, unresectable malignant solid neoplasm, unresectable merkel cell carcinoma, unresectable mucosal melanoma, unresectable skin squamous cell carcinoma, unresectable urothelial carcinoma