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Condition (MeSH)

Glucagonoma

ClinicalTrials.gov lists 33 trials for Glucagonoma or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 8.

MeSH D005935 Neoplasms Neoplasm C04 C06 C19 Listed by Orphanet as a rare disease
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Phase 1 Phase 1 9 Phase 2 Phase 2 19 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 1 Not applicable Not applicable 1 Observational Observational 2 Phase 1 Phase 1 9 Phase 2 Phase 2 19 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 1 Not applicable Not applicable 1 Observational Observational 2

Trials per phase

33 of the 33 trials are tagged with Glucagonoma itself; the rest are tagged with a narrower condition beneath it.

Get the Glucagonoma report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Glucagonoma trials start? (19)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Not applicable
  • Observational

Top of scale: 4

1996: 1 trials (Phase 1 1) 1998: 1 trials (Phase 1 1) 1999: 1 trials (Phase 1 1) 2000: 2 trials (Phase 1 2) 2001: 2 trials (Phase 2 2) 2003: 2 trials (Phase 2 2) 2004: 4 trials (Phase 2 3, Phase 1 1) 2005: 3 trials (Phase 2/3 1, Phase 2 2) 2006: 1 trials (Observational 1) 2007: 2 trials (Phase 3 1, Phase 2 1) 2008: 1 trials (Phase 2 1) 2009: 1 trials (Not applicable 1) 2010: 2 trials (Phase 2 1, Phase 1 1) 2012: 1 trials (Phase 2 1) 2013: 1 trials (Phase 2 1) 2014: 3 trials (Phase 2 3) 2016: 1 trials (Phase 2 1) 2017: 1 trials (Phase 1 1) 2018: 2 trials (Observational 1, Phase 1 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2018 2
2017 1
2016 1
2014 3
2013 1
2012 1
2010 2
2009 1
2008 1
2007 2

No forecast is made for this condition: it averages 0.0 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: none of the 33 trials evaluated at the 2026-10-09 snapshot is predicted and still running. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Glucagonoma trials in? (6)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 9
Phase 2 19
Phase 2/3 1
Phase 3 1
Not applicable 1
Observational 2

How many Glucagonoma trials are recruiting? (5)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Active, not recruiting 1
Completed 20
Terminated 8
Withdrawn 3
Unknown status 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Glucagonoma trials? (6)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 8
ECOG-ACRIN Cancer Research Group 2
Eastern Cooperative Oncology Group 2
Delcath Systems Inc. 1
INSYS Therapeutics Inc 1

Which drugs are being tested for Glucagonoma? (5)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
"Capecitabine" 4
EVEROLIMUS 4
Calcium Leucovorin 3
OXALIPLATIN 2
Vatalanib 2

Interventions as named in the registry (10)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
LAR Octreotide 4
SOC: Temozolomide 3
Fluorouracile 2
Bortezomib SC 2
Bevacizumab 1 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Glucagonoma trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Abdominal pain 29 5
Fatigue 29 4
Nausea 25 5
Vomiting 20 5
Diarrhea 17 5

Which publications cover Glucagonoma? (3)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
Induction of intestinal epithelial proliferation by glucagon-like peptide 2. Proceedings of the National Academy of Sciences of the United States of America 1996 Yes
Timing and extent of surgery in symptomatic and asymptomatic neuroendocrine tumors of the pancreas in MEN 1. Langenbeck's archives of surgery 2002 No
Interleukin-6 mediates host defense responses induced by abdominal surgery. Surgery 1993 No

Prevalence (6)

Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.

Prevalence
Orphanet disease Type Class Geography Jurisdiction Mapping relation
Glucagonoma Point prevalence <1 / 1 000 000 Europe Not stated Exact
Glucagonoma Point prevalence <1 / 1 000 000 Europe Not stated Unspecified
Glucagonoma Annual incidence <1 / 1 000 000 Europe Not stated Exact
Glucagonoma Annual incidence <1 / 1 000 000 Europe Not stated Exact
Glucagonoma Annual incidence <1 / 1 000 000 Europe Not stated Unspecified

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Glucagonoma 97280 Exact Orphadata Science knowledge files, Product 1
Glucagonoma 97280 Exact Orphanet Rare Disease Ontology (ORDO)

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: sub-conditions in mesh.

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