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Condition (MeSH)

Hand, Foot and Mouth Disease

ClinicalTrials.gov lists 59 trials for Hand, Foot and Mouth Disease or a narrower condition beneath it. Sinovac Biotech Co., Ltd has the most among industry and government lead sponsors, with 20.

MeSH D006232 Infections C01
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Phase 1 Phase 1 9 Phase 1/2 Phase 1/2 3 Phase 2 Phase 2 5 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 8 Phase 4 Phase 4 15 Not applicable Not applicable 9 Observational Observational 9 Phase 1 Phase 1 9 Phase 1/2 Phase 1/2 3 Phase 2 Phase 2 5 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 8 Phase 4 Phase 4 15 Not applicable Not applicable 9 Observational Observational 9

Trials per phase

59 of the 59 trials are tagged with Hand, Foot and Mouth Disease itself; the rest are tagged with a narrower condition beneath it.

Get the Hand, Foot and Mouth Disease report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Hand, Foot and Mouth Disease trials start? (15)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 9

2010: 6 trials (Observational 1, Not applicable 5) 2011: 7 trials (Not applicable 1, Phase 2 1, Phase 1 5) 2012: 4 trials (Phase 3 4) 2013: 2 trials (Observational 2) 2014: 2 trials (Phase 2 2) 2016: 3 trials (Phase 4 2, Phase 2 1) 2017: 6 trials (Observational 1, Phase 4 4, Phase 2 1) 2018: 4 trials (Phase 4 2, Phase 3 1, Phase 1 1) 2019: 9 trials (Phase 4 5, Phase 3 1, Phase 2/3 1, Phase 1/2 1, Phase 1 1) 2020: 1 trials (Phase 1 1) 2022: 3 trials (Observational 2, Phase 4 1) 2023: 3 trials (Observational 1, Phase 4 1, Phase 1/2 1) 2024: 3 trials (Observational 1, Not applicable 1, Phase 3 1) 2025: 3 trials (Observational 1, Phase 1/2 1, Phase 1 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 3
2025 3
2024 3
2023 3
2022 3
2020 1
2019 9
2018 4
2017 6
2016 3

No forecast is made for this condition: it averages 2.8 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 4 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Hand, Foot and Mouth Disease trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 9
Phase 1/2 3
Phase 2 5
Phase 2/3 1
Phase 3 8
Phase 4 15
Not applicable 9
Observational 9

How many Hand, Foot and Mouth Disease trials are recruiting? (5)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 4
Recruiting 3
Enrolling by invitation 1
Completed 37
Unknown status 14

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Hand, Foot and Mouth Disease trials? (4)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Sinovac Biotech Co., Ltd 20
Jiangsu Province Centers for Disease Control and Prevention 7
Enimmune Corporation 3
HK inno.N Corporation 2

Interventions as named in the registry (15)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
EV71 Vaccine 9
Western therapy 6
640Eu/0.5ml in children 2
Enterovirus Type 71 Vaccine (Vero Cell), Inactivated 2
0Eu/0.5ml in infants 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Hand, Foot and Mouth Disease? (19)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

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