Organization (Hospital)
Holland Bloorview Kids Rehabilitation Hospital
ClinicalTrials.gov lists Holland Bloorview Kids Rehabilitation Hospital as lead sponsor of 63 trials. It has 27 active development programs and 4 approved assets.
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Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 2 registered with a 2026 start date. The dashed outline is the pace from the 2 registered with a start date through September, planned starts included, not adjusted; not a forecast. No forecast is made for this organization: it averages 4.8 trial starts a year over the five years to September, under the 5 a year the method needs.
This page covers Holland Bloorview Kids Rehabilitation Hospital: 63 lead-sponsored trials and 2 legal-entity registrations.
Disease areas (37)
Shown in this order: most trials first.
| Disease area | Trials |
|---|---|
| Autism Spectrum Disorder | 27 |
| Cerebral Palsy | 27 |
| Brain Injuries | 11 |
| Autistic Disorder | 9 |
| Brain Concussion | 5 |
Showing 5 of 37 disease areas.
Trials by start year as sponsor or collaborator (20)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 3 |
| 2024 | 5 |
| 2023 | 5 |
| 2022 | 9 |
| 2021 | 2 |
| 2020 | 4 |
| 2019 | 2 |
| 2018 | 9 |
| 2017 | 5 |
Showing 10 of 20 years.
Prediction, not a registry value: median of 36 months from start to primary completion across 10 trials still running at the 2026-10-09 snapshot; registered median of 21 months across 40 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Active development programs (27)
Shown in this order: max phase, then active trials.
| Drug | Disease area | Max phase | Trials |
|---|---|---|---|
| METFORMIN | Autism Spectrum Disorder | Phase 3 | 1 |
| Rett-T | Intellectual Disability | Phase 2 | 1 |
| Rett-T | Rett Syndrome | Phase 2 | 1 |
| Sertraline | Autism Spectrum Disorder | Phase 2 | 1 |
| Sertraline | Anxiety Disorders | Phase 2 | 1 |
Showing 5 of 27 active programs.
Approved assets (4)
Shown in this order: max phase first.
| Drug | Trials |
|---|---|
| METFORMIN | 2 |
| Riluzole | 1 |
| Sertraline | 1 |
| FLUOXETINE | 1 |
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 52% hit target (n=23) | 32% on time (n=19) |
Journals published in (109)
Shown in this order: most published in first.
| Journal | Publications |
|---|---|
| Journal of autism and developmental disorders | 12 |
| Pediatrics | 12 |
| Journal of the American Academy of Child and Adolescent Psychiatry | 9 |
| Developmental medicine and child neurology | 8 |
| Journal of child and adolescent psychopharmacology | 7 |
Showing 5 of 109 journals.
US granted patents (1)
Patents are not classified by disease area in the source, so this is the organization's overall portfolio, not a split by disease.
| US patents granted | Granted in the last 5 years | Most recent grant |
|---|---|---|
| 10 | 4 | 2024-01-23 |
Organization relationships (27)
Shown in this order: most evidence first.
| Related organization | Relationship | Evidence |
|---|---|---|
| The Hospital for Sick Children | Co sponsors trial with | 7 |
| Evdokia Anagnostou | Co sponsors trial with | 2 |
| University of California System | Co sponsors trial with | 2 |
| Ontario Brain Institute | Co sponsors trial with | 2 |
| Children's Hospital of Eastern Ontario | Co sponsors trial with | 2 |
Showing 5 of 27 relationships.
Latest dated events (86)
Shown in this order: newest first.
| Date | Event | Source |
|---|---|---|
| 2026-08-24 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-02-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-12-06 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-10-22 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2025-09-05 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
Showing 5 of 86 events.
Biomarker capability evidence (33)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| ADO | Trial sponsor | Named in trial inclusion criteria |
| FDPS | Trial sponsor | Named in trial inclusion criteria |
| FES | Trial sponsor | Named in trial inclusion criteria |
| FES | Trial sponsor | Named in trial inclusion criteria |
| PPCS | Trial sponsor | Named in trial inclusion criteria |
Showing 5 of 33 evidence rows.
Biomarkers this organization publishes on (91)
Shown in this order: most publications first.
Showing 5 of 91 biomarkers.
Not on this page
Checked, with nothing recorded for this organization: companies grouped under this page, related companies not grouped here, sec-reported annual financials, financing and grant events, fda warning letters, fda untitled letters, fda inspection record, fda recalls, fda import refusals, manufacturing and distribution sites, climate targets, as filed, workforce and board diversity, as filed, and clia clinical laboratory certificates.