Organization (Nonprofit)
INSTITUT CURIE
ClinicalTrials.gov lists INSTITUT CURIE as lead sponsor of 134 trials. It has 107 active development programs and 24 approved assets.
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Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 7 registered with a 2026 start date. The hollow diamonds on the dashed line are a forecast of the full-year count, planned starts included: about 8 in 2026 and about 8 in 2027, the average of the 24 months through September, counted as registered and carried forward. The columns, the lighter one included, count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. This method has not been backtested on organizations. In backtests on conditions with as many trial starts a year as this organization (5 to 20), forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
This page covers INSTITUT CURIE: 134 lead-sponsored trials and 2 legal-entity registrations.
Disease areas (72)
Shown in this order: most trials first.
| Disease area | Trials |
|---|---|
| Breast Neoplasms | 47 |
| Melanoma | 15 |
| Neoplasm Metastasis | 13 |
| Uveal Melanoma | 13 |
| Triple Negative Breast Neoplasms | 9 |
Showing 5 of 72 disease areas.
Trials by start year as sponsor or collaborator (22)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2026 (partial year) | 7 |
| 2025 | 8 |
| 2024 | 15 |
| 2023 | 13 |
| 2022 | 15 |
| 2021 | 19 |
| 2020 | 9 |
| 2019 | 5 |
| 2018 | 6 |
| 2017 | 8 |
Showing 10 of 22 years.
Prediction, not a registry value: median of 36 months from start to primary completion across 22 trials still running at the 2026-10-09 snapshot; registered median of 40 months across 90 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Active development programs (107)
Shown in this order: max phase, then active trials.
| Drug | Disease area | Max phase | Trials |
|---|---|---|---|
| Endocrine Therapy | Neoplasm Metastasis | Phase 3 | 1 |
| AG chemotherapy | Breast Neoplasms | Phase 3 | 1 |
| AG chemotherapy | Neoplasm Metastasis | Phase 3 | 1 |
| Endocrine Therapy | Breast Neoplasms | Phase 3 | 1 |
| DEXMEDETOMIDINE | Breast Neoplasms | Phase 3 | 1 |
Showing 5 of 107 active programs.
Approved assets (24)
Shown in this order: max phase first.
| Drug | Trials |
|---|---|
| Ropivacaïne Hydrochloride by Erector Spinae block | 1 |
| Ropivacaïne Hydrochloride by Paravertebral block | 1 |
| Chlorhydrate de Ropivacaine | 1 |
| Ropivacaine | 2 |
| DEXMEDETOMIDINE | 1 |
Showing 5 of 24 approved assets.
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 57% hit target (n=58) | 31% on time (n=65) |
Journals published in (75)
Shown in this order: most published in first.
| Journal | Publications |
|---|---|
| Journal of clinical oncology : official journal of the American Society of Clinical Oncology | 9 |
| European journal of cancer (Oxford, England : 1990) | 5 |
| Annals of oncology : official journal of the European Society for Medical Oncology | 4 |
| BMC cancer | 4 |
| British journal of cancer | 4 |
Showing 5 of 75 journals.
US granted patents (1)
Patents are not classified by disease area in the source, so this is the organization's overall portfolio, not a split by disease.
| US patents granted | Granted in the last 5 years | Most recent grant |
|---|---|---|
| 176 | 31 | 2025-11-25 |
Organization relationships (61)
Shown in this order: most evidence first.
| Related organization | Relationship | Evidence |
|---|---|---|
| Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | Co sponsors trial with | 4 |
| Unicancer | Co sponsors trial with | 4 |
| Gustave Roussy, Cancer Campus, Grand Paris | Co sponsors trial with | 4 |
| Groupe Hospitalier Pitie-Salpetriere | Co sponsors trial with | 3 |
| National Cancer Institute, France | Co sponsors trial with | 2 |
Showing 5 of 61 relationships.
Latest dated events (348)
Shown in this order: newest first.
| Date | Event | Source |
|---|---|---|
| 2026-10-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-08-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-06-23 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-03-05 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-03-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
Showing 5 of 348 events.
Biomarker capability evidence (259)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| ALB | Trial sponsor | Named in trial inclusion criteria |
| ALB | Trial sponsor | Named in trial inclusion criteria |
| ALK | Trial sponsor | Named in trial inclusion criteria |
| ATM | Trial sponsor | Named in trial inclusion criteria |
| BLVRB | Trial sponsor | Named in trial inclusion criteria |
Showing 5 of 259 evidence rows.
Biomarkers this organization publishes on (982)
Shown in this order: most publications first.
Showing 5 of 982 biomarkers.
On Scientist.com
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