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Clinical trial

A Phase 1 Open-label, Multicenter, Dose-ranging Study to Investigate Safety and Tolerability, Efficacy, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Types

NCT06034860 is registered in ClinicalTrials.gov with Molecular Templates, Inc. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1 Open-label, Multicenter, Dose-ranging Study to Investigate Safety and Tolerability, Efficacy, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of MT-8421 as Monotherapy and in Combination With Nivolumab in Patients With Selected Advanced Solid Cancer Types
Lead sponsor
Molecular Templates, Inc.
Phase
Phase 1
Overall status
Terminated
Start date
November 1, 2023
Completion date
October 31, 2024
Enrollment
15 (actual)
Sites
5

Conditions

As the registry lists them; a condition with its own page is linked.

cervical cancer, esophageal squamous cell carcinoma, hepatocellular carcinoma, melanoma, mesothelioma, microsatellite instability high, mismatch repair deficiency, non small cell lung cancer, renal cell carcinoma, squamous cell carcinoma of head and neck, urothelial carcinoma