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Organization (Academic)

MASSACHUSETTS INSTITUTE OF TECHNOLOGY

ClinicalTrials.gov lists MASSACHUSETTS INSTITUTE OF TECHNOLOGY as lead sponsor of 33 trials, counting the companies grouped under it. MASSACHUSETTS INSTITUTE OF TECHNOLOGY itself has 1 approved asset.

US Academic
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13 0 1990 2027

Trials started per year with this organization as sponsor or collaborator, 1990 onward. Companies grouped under this one are not included. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.

2026 is partial: 11 registered with a 2026 start date. The hollow diamonds on the dashed line are a forecast of the full-year count, planned starts included: about 10 in 2026 and about 9 in 2027, the average of the 24 months through September, counted as registered and carried forward. The columns, the lighter one included, count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. This method has not been backtested on organizations. In backtests on conditions with as many trial starts a year as this organization (5 to 20), forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored. The 2026 forecast is below the 11 already registered with a 2026 start date: at the cutoff, 3 trials were already registered to start in October to December, more than the method's monthly average allows for, and the method does not use those planned starts. 1 trial is registered to start in 2027 or later.

Logo Matthew Carter and others, owned by Massachusetts Institute of Technology, via Wikimedia Commons, Public domain. Shown to identify the organization; it may be a registered trademark.

This page covers MASSACHUSETTS INSTITUTE OF TECHNOLOGY and 1 company grouped under it: 33 lead-sponsored trials (33 its own, 0 in the grouped companies) and 4 legal-entity registrations (2 its own, 2 in the grouped companies).

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Companies grouped under this page (1)

Companies grouped under this page
Company Lead trials Legal entities
Whitehead Institute for Biomedical Research 0 2

Disease areas (83)

Shown in this order: most trials first.

Disease areas
Disease area Trials
Anxiety Disorders 8
Alzheimer Disease 7
Dementia 7
Influenza, Human 7
Autism Spectrum Disorder 6

Trials by start year as sponsor or collaborator (23)

Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Show the table of trials by start year as sponsor or collaborator
Trials by start year as sponsor or collaborator
Year Trials started
2026 (partial year) 11
2025 9
2024 8
2023 9
2022 9
2021 13
2020 7
2019 10
2018 9
2017 5

Prediction, not a registry value: median of 35 months from start to primary completion across 7 trials still running at the 2026-10-09 snapshot; registered median of 15 months across 16 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

Approved assets (1)

Approved assets
Drug Trials
Cannabidiol 1

Sponsor delivery record (1)

Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.

Sponsor delivery record
Enrollment Timeline
50% hit target (n=8) 50% on time (n=10)

Journals published in (200)

Shown in this order: most published in first.

Journals published in
Journal Publications
Proceedings of the National Academy of Sciences of the United States of America 8
Ophthalmology 7
PloS one 7
The New England journal of medicine 7
Journal of occupational and environmental medicine 6

US granted patents (1)

Patents are not classified by disease area in the source, so this is the organization's overall portfolio, not a split by disease.

US granted patents
US patents granted Granted in the last 5 years Most recent grant
8,736 1,418 2025-12-30

Financing and grant events (1,429)

Shown in this order: most recent first.

Financing and grant events
Date Round type Amount (USD) Source
2025-09-23 NIH grant 1,479,335 Reporter
2025-09-22 NIH grant 2,002,011 Reporter
2025-09-19 NIH grant 403,752 Reporter
2025-09-18 NIH grant 92,232 Reporter
2025-09-18 NIH grant 406,151 Reporter

Organization relationships (30)

Shown in this order: most evidence first.

Organization relationships
Related organization Relationship Evidence
Mass General Brigham Co sponsors trial with 3
Government of the United States of America Co sponsors trial with 1
Comunidad de Madrid Co sponsors trial with 1
Beth Israel Deaconess Medical Center Co sponsors trial with 1
University of California System Co sponsors trial with 1

Latest dated events (10,295)

Shown in this order: newest first.

Latest dated events
Date Event Source
2027-01-01 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))
2026-12 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))
2026-11 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))
2026-10-01 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))
2026-09-28 Trial started Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI))

Biomarker capability evidence (40)

Shown in this order: tier desc, then gene symbol.

Biomarker capability evidence
Gene Role Evidence
BCHE Trial sponsor Named in trial inclusion criteria
BRAF Trial collaborator Named in trial inclusion criteria
DAND5 Trial collaborator Named in trial inclusion criteria
ERBB2 Trial collaborator Named in trial inclusion criteria
ESR1 Trial collaborator Named in trial inclusion criteria

Biomarkers this organization publishes on (1,329)

Shown in this order: most publications first.

Biomarkers this organization publishes on
Biomarker Publications
CD4 38
CD8A 30
IFNG 30
TNF 26
TP53 25

Not on this page

Checked, with nothing recorded for this organization: related companies not grouped here, active development programs, sec-reported annual financials, fda warning letters, fda untitled letters, fda inspection record, fda recalls, fda import refusals, manufacturing and distribution sites, climate targets, as filed, workforce and board diversity, as filed, and clia clinical laboratory certificates.