Organization (Academic)
University of Sheffield
ClinicalTrials.gov lists University of Sheffield as lead sponsor of 75 trials. It has 1 active development program and 1 approved asset.
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Trials started per year with this organization as sponsor or collaborator, 1990 onward. The series also counts trials where the organization is a collaborator; the lead-sponsor trial count does not.
2026 is partial: 9 registered with a 2026 start date. The hollow diamonds on the dashed line are a forecast of the full-year count, planned starts included: about 10 in 2026 and about 13 in 2027, the average of the 24 months through September, counted as registered and carried forward. The columns, the lighter one included, count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. This method has not been backtested on organizations. In backtests on conditions with as many trial starts a year as this organization (5 to 20), forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
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This page covers University of Sheffield: 75 lead-sponsored trials and 2 legal-entity registrations.
Disease areas (160)
Shown in this order: most trials first.
| Disease area | Trials |
|---|---|
| Hypertension, Pulmonary | 10 |
| Bone Diseases, Metabolic | 9 |
| Osteoporosis | 9 |
| Anxiety Disorders | 8 |
| Hypertension | 7 |
Showing 5 of 160 disease areas.
Trials by start year as sponsor or collaborator (25)
Shown in this order: most recent first. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Show the table of trials by start year as sponsor or collaborator
| Year | Trials started |
|---|---|
| 2026 (partial year) | 9 |
| 2025 | 12 |
| 2024 | 18 |
| 2023 | 11 |
| 2022 | 10 |
| 2021 | 17 |
| 2020 | 13 |
| 2019 | 24 |
| 2018 | 11 |
| 2017 | 13 |
Showing 10 of 25 years.
Prediction, not a registry value: median of 22 months from start to primary completion across 7 trials still running at the 2026-10-09 snapshot; registered median of 8 months across 41 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
Active development programs (1)
| Drug | Disease area | Max phase | Trials |
|---|---|---|---|
| Not applicable- observational study | Amyotrophic Lateral Sclerosis | Not reported | 1 |
Approved assets (1)
| Drug | Trials |
|---|---|
| Zoledronic Acid | 1 |
Sponsor delivery record (1)
Enrollment hit target: the share of this sponsor's lead-sponsored trials whose actual enrollment reached the planned enrollment. On time: the share whose actual primary completion date was no later than the planned date. Each share counts only trials where we observed an estimated figure before the actual one, and n is that number of trials. Below 5 trials the count is shown as a fraction, not a percentage.
| Enrollment | Timeline |
|---|---|
| 33% hit target (n=21) | 47% on time (n=19) |
Journals published in (312)
Shown in this order: most published in first.
| Journal | Publications |
|---|---|
| Trials | 14 |
| BMJ open | 13 |
| BMJ (Clinical research ed.) | 11 |
| The British journal of dermatology | 11 |
| Caries research | 9 |
Showing 5 of 312 journals.
Financing and grant events (5)
Shown in this order: most recent first.
| Date | Round type | Amount (USD) | Source |
|---|---|---|---|
| 2025-04-17 | NIH grant | 496,470 | Reporter |
| 2024-04-19 | NIH grant | 718,625 | Reporter |
| 2022-09-14 | NIH grant | 251,699 | Reporter |
| 2020-07-22 | NIH grant | 124,298 | Reporter |
| 2020-05-01 | NIH grant | 461,888 | Reporter |
Organization relationships (47)
Shown in this order: most evidence first.
| Related organization | Relationship | Evidence |
|---|---|---|
| National Institute for Health Research, United Kingdom | Co sponsors trial with | 5 |
| University Hospital, Tours | Co sponsors trial with | 2 |
| Gouvernement de la République française | Co sponsors trial with | 2 |
| University College London Hospitals | Co sponsors trial with | 2 |
| Humanitas Mirasole SpA | Co sponsors trial with | 2 |
Showing 5 of 47 relationships.
Latest dated events (223)
Shown in this order: newest first.
| Date | Event | Source |
|---|---|---|
| 2026-12 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-10 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-09 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-09-01 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
| 2026-05-27 | Trial started | Clinical trials (ClinicalTrials.gov) (ClinicalTrials.gov, U.S. National Library of Medicine; AACT database, Clinical Trials Transformation Initiative (CTTI)) |
Showing 5 of 223 events.
Biomarker capability evidence (140)
Shown in this order: tier desc, then gene symbol.
| Gene | Role | Evidence |
|---|---|---|
| ACE | Trial collaborator | Named in trial inclusion criteria |
| ACTG1 | Trial collaborator | Named in trial inclusion criteria |
| AGT | Trial collaborator | Named in trial inclusion criteria |
| AMD1 | Trial collaborator | Named in trial inclusion criteria |
| APOH | Trial collaborator | Named in trial inclusion criteria |
Showing 5 of 140 evidence rows.
Biomarkers this organization publishes on (1,006)
Shown in this order: most publications first.
Showing 5 of 1,006 biomarkers.
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